Green synthesis of morpholine-2-thione by multicomponent reaction of aziridines

Ghasemi, Narges; Sharifi, Samaneh sadat

doi:10.30495/iranjoc.2023.706233

Manuscript ID : 706233 Visit : 235 Page: 3627 - 3630

10.30495/iranjoc.2023.706233

Article Type: Original Research

Green synthesis of morpholine-2-thione by multicomponent reaction of aziridines

Subject Areas : Iranian Journal of Organic Chemistry

Narges Ghasemi ¹ , Samaneh sadat Sharifi ²

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Received: 2023-09-17 Accepted : 2023-09-17 Published : 2023-08-01

Keywords: multi component reaction, Aziridin, Carbone disulfide, Nitro methane,

Abstract :

A series of substituted morpholine-2-thione derivatives were synthesized via one-pot multicomponent reactions of nitromethane, carbon disulfide and aziridine in the presence of Et3N under solvent-free conditions. Particularly valuable features of this method include high yields of products, broad substrate scope, short reaction time and straightforward procedure.

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Mechanistic Investigation of the [1+4] Cycloaddition Reaction Between Alkyl Isocyanides and 3-benzylidene-2,4-pentanedione: A Theoretical Study
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Synthesis and characterization of PTS and PDATS: Two maiden functionalized energetic polymers having tetrazole and triazine rings
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BF3 catalyzed hydroarylation reactions of arylsubstituted alkynes with different electron rich arenes
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Synthesis of some 3-indolyl heterocycles and evaluation of its antimicrobial activity
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1,3,4-Thiadiazole rings as π-spacers in triphenylamine based dyes: A density functional theory study of reactivity, UV/Visible spectra, structural and optical properties
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Graphical Abstract
Print Date : 2014-05-01

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Green synthesis of morpholine-2-thione by multicomponent reaction of aziridines