Green synthesis of imidazole derivatives using multicomponent reactions

Ghasemi, Narges

doi:10.30495/iranjoc.2023.704941

Manuscript ID : 704941 Visit : 130 Page: 3601 - 3605

10.30495/iranjoc.2023.704941

Article Type: Original Research

Green synthesis of imidazole derivatives using multicomponent reactions

Subject Areas : Iranian Journal of Organic Chemistry

Narges Ghasemi ¹

1 -

Received: 2023-08-14 Accepted : 2023-08-14 Published : 2023-05-01

Keywords: multi component reaction, Ninhydrin, Primary amine, Arylisothiocyanates, Dialkyl acetylenedicarboxylates,

Abstract :

An efficient synthesis of functionalized imidazoles via a one-pot reaction between ninhydrin, primary alkylamines, arylisothiocyanates, acetylenic esters and N-formylmorpholine as green solvent is described.

References:

Mechanistic Investigation of the [1+4] Cycloaddition Reaction Between Alkyl Isocyanides and 3-benzylidene-2,4-pentanedione: A Theoretical Study
Print Date : 2020-07-17
Synthesis and characterization of PTS and PDATS: Two maiden functionalized energetic polymers having tetrazole and triazine rings
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BF3 catalyzed hydroarylation reactions of arylsubstituted alkynes with different electron rich arenes
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Synthesis of some 3-indolyl heterocycles and evaluation of its antimicrobial activity
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1,3,4-Thiadiazole rings as π-spacers in triphenylamine based dyes: A density functional theory study of reactivity, UV/Visible spectra, structural and optical properties
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Graphical Abstract
Print Date : 2014-05-01

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Green synthesis of imidazole derivatives using multicomponent reactions