Green synthesis of naphthiridinone using multicomponent reaction of Melderumʼs acid and 4-aminoquinoline-2-one

Shams Najafi, Seyyed Jalal; Ghazvini, Maryam; Navabi, Atefeh

Manuscript ID : 699704 Visit : 169 Page: 3431 - 3434

Article Type: Original Research

Green synthesis of naphthiridinone using multicomponent reaction of Melderumʼs acid and 4-aminoquinoline-2-one

Subject Areas : Iranian Journal of Organic Chemistry

Seyyed Jalal Shams Najafi ¹ , Maryam Ghazvini ² , Atefeh Navabi ³

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Received: 2023-02-26 Accepted : 2023-02-26 Published : 2022-11-01

Keywords: Solvent-free, Naphthiridinone, Acetophenone derivatives, Meldrum’s acid, 4-aminocoumarin, Dimethylcarbonate,

Abstract :

An efficient synthesis of naphthiridinone derivatives via reaction of 4-aminoquinoline-2-one, Melderum acid and ketones under solnent free conditions and room temperatureis described.

References:

Mechanistic Investigation of the [1+4] Cycloaddition Reaction Between Alkyl Isocyanides and 3-benzylidene-2,4-pentanedione: A Theoretical Study
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Synthesis and characterization of PTS and PDATS: Two maiden functionalized energetic polymers having tetrazole and triazine rings
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BF3 catalyzed hydroarylation reactions of arylsubstituted alkynes with different electron rich arenes
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Synthesis of some 3-indolyl heterocycles and evaluation of its antimicrobial activity
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1,3,4-Thiadiazole rings as π-spacers in triphenylamine based dyes: A density functional theory study of reactivity, UV/Visible spectra, structural and optical properties
Print Date : 2015-11-01
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Print Date : 2014-05-01

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Green synthesis of naphthiridinone using multicomponent reaction of Melderumʼs acid and 4-aminoquinoline-2-one