Discussion on the regioselectivity of aminolysis of 5-bromo-2,4- dichloro-6-methylpyrimidine in ethanole

Subject Areas :

Abdolhassan  Doulah ¹ (Department of Nursing, Faculty of Nursing and Midwifery, Islamic Azad University, Ahvaz Branch, Ahvaz)
Hossein  Eshtiagh-Hosseini ² (Department of Chemistry, School of Sciences, Ferdowsi University of Mashhad, Mashhad, P.O. Box 917791436, Iran)
Masoud  Mirzaei ³ (Department of Chemistry, School of Sciences, Ferdowsi University of Mashhad, Mashhad, P.O. Box 917791436, Iran)
Ali  Fazlara ⁴ (Department of Biology, Shahid Chamran University of Ahvaz, Ahvaz, Iran)

Received: 2016-05-25 Accepted : 2016-05-25 Published : 2011-05-01

Keywords: Protein, Hybrid, Proline, Hydrogen bonding, Polyoxometallates, Molybdenum, Keggin, Peptide,

Abstract :

Crystallographic data analyses indicate that three types of prolinium cations, along with two types of hydrogen bonding, produce and stabilize the helical structure of triprolinium 12-phosphomolybdate. There are similarities between this organic-inorganic compound and peptides/proteins. The stronger “conventional” hydrogen bonds and the less common C-H…O attractions play critical roles in generating and stabilizing the DNA-like network.