Selective and facile Synthesis of 2-Aminothiophenes Using Na2CaP2O7 as base Nano-Catalyst

Subject Areas :

Iman Khosravi ¹ (Department of Chemistry, Qeshm Branch, Islamic Azad University, Qeshm, Iran.)
Elham Rastegar ² (Department of Chemistry, Qeshm Branch, Islamic Azad University, Qeshm, Iran.)
Melika Eftekhar ³ (Department of Chemistry, Qeshm Branch, Islamic Azad University, Qeshm, Iran.)
Farid Moeinpour ⁴ (Department of Chemistry, Bandar Abbas Branch, Islamic Azad University, Bandar Abbas, Iran)

Received: 2022-03-14 Accepted : 2022-03-14 Published : 2022-03-01

Keywords: Nanocatalyst, Gewald reaction, 2-Aminothiophenes, Na2CaP2O7,

Abstract :

In the study we reported synthesis of 2-aminothiophene derivatives in pure water using nano-structured Na2CaP2O7. Our results indicated that this heterogeneous catalyst performed good selectivity and catalytic activity in the synthesis of substituted 2- aminothiophene through Gewald reaction in water. The noticeable benefits of this procedure rely on several factors including: a simple method, mildness conditions, short time of reaction, operational simplicity and low cost.