Employment of the magnetic nano-catalyst Fe3O4@SiO2@CS@ PO(OH)2/Cu(II) for the amination of alcohols
Subject Areas :
1 - Department of Chemistry, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran.
Keywords: Magnetic nanocatalyst, Core-shell nanoparticle, Alcohol, Catalyst optimization, AMINATION,
Abstract :
In this research study, the Fe3O4@SiO2@CS@ PO(OH)2/Cu(II) core-shell nanoparticle serves as a highly effective magnetic catalyst. Its purpose is to efficiently convert a variety of alcohols, whether they contain electron-donating or electron-withdrawing groups, into their corresponding amine derivatives. Benzylamine and ammonia were employed as the amination agents. The optimization process studied various factors, including the presence and kind of a base, reaction temperature, time of reaction, type of transition metal, and amount of catalyst to identify the most favorable parameters. The optimal conditions were observed when using 0.3 mmol of catalyst liganded to Cu(II) under reflux conditions for a duration of 5-24 h corresponding to the substrate in the presence of K2CO3. The results of the study revealed that electron-donating groups have a positive impact on the reaction rate, whereas electron-withdrawing groups, such as nitro, negatively influence the overall yield. Additionally, this reaction process displayed remarkable efficiency. It offers exceptional practicality in organic chemistry and industrial applications, primarily due to the ease of separating the catalyst using an external magnetic field, its stability, and its ability to be reused multiple times.