Molecular Markers for Fertility in Farm Animals
Subject Areas : CamelK.G.M. Mahmoud 1 , M.F. Nawito 2
1 - Department of Animal Reproduction and A.I. National Research Center, Dokki, Tahrir Street, 12622 Giza, Egypt
2 - Department of Animal Reproduction and A.I. National Research Center, Dokki, Tahrir Street, 12622 Giza, Egypt
Keywords:
Abstract :
A genetic marker is a gene or DNA sequence with known localization on a chromosome. It can be de-scribed as a variation that can be measured or detected by a suitable method, and can be used subsequently to detect the presence of a specific genotype. Such variations occurring at chromosomal or DNA level can serve as genetic markers. The progress in development of molecular markers suggests their potential use for genetic improvement in livestock species. Animal fertility is a measure of reproductive success. In males, it can be defined as the ability of a male to produce semen that will result in a successful pregnancy. In fe-males, it can be defined as the ability of female to cycle and conceive normally to produce a viable off-spring. Such a complex feature is under the influence of numerous genes, working together to produce func-tional gametes, promote early embryonic and fetal development and finally the delivery of a healthy off-spring. The heritability is relatively low for fertility so reproductive traits in general are well-suited for ap-plication of marker-assisted selection (MAS). Animal fertility is one of the most important economical traits in animal production. Reproductive performance is controlled by the genetic make-up of the female and male, but in general it is largely affected by environment. Phenotypic selection for reproductive traits can only be carried out after puberty while marker-assisted selection could be a tool of choice to improve animal fertility. The possibility of exerting selection criteria at the molecular level shortens the generation interval as the selection decision can take place early in the life of an animal. Moreover, in consideration of the sex-limited nature of reproductive traits, genotypic information could allow for selection in the gender in which the trait cannot be directly observed. Accordingly, there has been considerable interest in mapping and identifying genes involved in the regulation of reproductive traits and in elucidating their expression patterns. The current review aimed to discuss the efforts being made and the approaches currently used in the field of molecular markers and their application to fertility in farm animals.
Abdel Dayem A.M.H., Mahmoud K.Gh.M., Nawito M.F., Ayoub M.M. and Scholkamy T.H. (2009). Fertility evaluation in Egyptian buffalo bulls using zona pellucida binding and in vitro fertilization assays. Livest. Sci. 122, 193-198.
Abe S., Miyake Y.I., Kageyama S.I., Watanabe G., Taya K. and Kawakura K. (1999). Deletion of the Sry region on the Y chromosome detected in a case of equine gonadal hypoplasia (XY female) with abnormal hormonal profiles. Equine Vet. J. 31, 336-338.
Achermann J.C. and Jameson J.L. (1999). Fertility and infertility: genetic contributions from the hypothalamic-pituitary-gonadal axis. Mol. Endocrinol. 13, 812-818.
Aiman J., Mcasey M. and Harms L. (1998). Serum and seminal plasma prolactin concentrations in men with normospermia, oligospermia, or azoospermia. Fertil. Steril.49, 133-137.
Akira S. (1999). Functional roles of STAT family proteins: lessons from knockout mice. Stem Cells. 17, 138-146.
AL-Tonbary Y., Abdel-Razek N., Zaghloul H., Metwaly S., EL-Deek B. and EL-Shawaf R. (2004). HLA class II polymorphism in Egyptian children with lymphomas. Hematology. 9, 139-145.
Appa Rao K.B.C. and Totey S.M. (1999). Cloning and sequencing of buffalo male-specific repetitive DNA: sexing of in vitro developed buffalo embryos using multiplex and nested polymerase chain reaction. Theriogenology. 51, 785-797.
Ashwell M.S., Heyen D.W., Weller J.I., Ron M., Sonstegard T.S., Van Tassell C.B. and Lewin H.A. (2005). Detection of quantitative trait loci influencing conformation traits and calving ease in Holstein-Friesian cattle. J. Dairy Sci. 88, 4111-4119.
Asif M., Awan A. R., Babar M. E., Ali A., Firyal S. and Khan Q. M. (2009). Development of genetic marker for molecular detection of Brucella abortus. PakistanJ. Zool. Suppl. Ser. 9, 267-271.
Avidan N., Tamary H., Dgany O., Cattan D., Pariente A., Thulliez M., Borot N., Moati L., Barthelme A., Shalmon L., Krasnov T., Ben-Asher E., Olender T., Khen M., Yaniv I., Zaizov R., Shalev H., Delaunay J., Fellous M., Lancet D. and Beckmann J.S. (2003). CATSPER2, a human autosomal nonsyndromic male infertility gene. Eur. J. Hum. Genet. 11, 497-502.
Ben Jemaa S., Fritz S., Guillaume F., Druet T., Denis C., Eggen A. and Gautier M. (2008). Detection of quantitative trait loci affecting non return rate in French dairy cattle. J. Anim. Breed. Genet. 125, 280-288.
Berglund B. (2008). Genetic improvement of dairy cow reproductive performance. Reprod. Domest. Anim. 43, 89-95.
Berry D.P., Buckley F., Dillon P., Evans R.D., Rath M. and Veerkamp R.F. (2003). Genetic relationships among body condition score, body weight, milk yield, and fertility in dairy cows. J. Dairy Sci. 86, 2193-2204.
Beuzen N.D., Stear M.J. and Chang K.C. (2000). Molecular markers and their use in animal breeding. Vet. J. 160, 42-52.
Bishop M.D., Simmen R.C.M., Simmen F.A. and DavisM.E.(1989). The relationship of insulin-like growth factor-I with postweaning performance in Angus beef cattle. J. Anim. Sci. 67, 2872-2880.
Bo-Abbas Y., Acierno J.S.J.R., Shagoury J.K., CrowleyW.F.J.R. and Seminara S.B. (2003). Autosomal recessive idiopathic hypogonadotropic hypogonadism: genetic analysis excludes mutations in the gonadotropin-releasing hormone (GnRHR) and GnRHR receptor genes. J. Clin. Endocrinol. Metab. 88, 2730-2737.
Boichard D., Grohs C., Bourgeois F., Cerqueira F., Faugeras R., Neau A., Rupp R., Amigues Y., Boscher M.Y. and Leveziel H. (2003). Detection of genes influencing economic traits in three French dairy cattle breeds. Genet. Sel. Evol. 35, 77-101.
Bole-Feysot C., Goffin V., Edery M., Binart N. and Kelly P.A. (1998). Prolactin (PRL) and its receptor: actions, signal transduction pathways and phenotypes observed in PRL receptor knockout mice. Endocrinol. Rev. 19, 225-268.
Boligon A.A., Baldi F. and Albuquerque L.G. (2010). Estimates of genetic parameters for scrotal circumference using random regression models in Nelore cattle. Livest. Sci. (in press).
Bouters R., Vandeplassche M. and De Moor A. (1972). An intersex (male pseudohermaphrodite) horse with 64 XX-65 XXY mosaicism. Equine Vet. J. 4, 150-153.
Bovenhuis H., Van Arendonk L.A.M., Davis G., Elsen J.M., Haley C.S., Hill W.G., Baret P.V., Hetzel D.J.S. and Nicholas F.W. (1997). Detection and mapping of quantitative trait loci in farm animals. Livest. Prod. Sci. 52, 135-144.
Brym P., Kaminski S. and Rusc A. (2004). New SSCP polymorphism within bovine STAT5A gene and its associations with milk performance traits in Black-and-White and Jerseycattle. J. Appl. Genet. 45, 445-452.
Bugno M., Klukowska J., Slota E., Tischner M. and Switonski M. (2003). A sporadic case of the sex-reversed mare (64, XY; SRY-negative): molecular and cytogenetic studies of the Y chromosome. Theriogenology. 59, 1597-1603.
Canto P., Escudero I., Soderlund D., Nishimura E., Carranza-Lira S., Gutierrez J., Nava A. and Mendez J.P. (2003). A novel mutation of the insulin-like 3 gene in patients with cryptorchidism. J. Hum. Genet. 48, 86-90.
Chen Y., Cann M.J., Litvin T.N., Iourgenko V., Sinclair M.L., Levin L.R. and Buck J. (2000). Soluble adenylyl cyclase as an evolutionarily conserved bicarbonate sensor. Science. 289, 625-628.
Cho B.N., Mcmullen M.L., Pei L., Yates C.J. and Mayo K.E. (2001). Reproductive deficiencies in transgenic mice expressing the rat inhibin alpha-subunit gene. Endocrinology. 142, 4994-5004.
Chowdhary B.P. and Raudsepp T. (2008). The horse genome derby: racing from map to whole genome sequence. Chromosome Res. 16, 109-127.
Chowdhary B.P., Paria N. and Raudsepp T. (2008). Potential applications of equine genomics in dissecting diseases and fertility. Anim. Reprod. Sci. 107, 208-218.
Chrenek P., Boulanger L., Heyman Y., Uhrin P., Laurincik J., Bulla J. and Renard J.P. (2001). Sexing and multible genotype analysis from a single cell of bovine embryo. Theriogenology. 55, 1071-1081.
Cohen D.J., Ellerman D.A. and Cuasnicu P.S. (2000). Mammalian sperm-egg fusion: evidence that epididymal protein DE plays a role in mouse gamete fusion. Biol. Reprod. 63, 462-468.
Cohen D.P. (2000). Molecular evaluation of the gonadotropin-releasing hormone receptor. Semin. Reprod. Med. 18, 11-16.
Coyral-Castel S., Raméa C., Monniauxa D., Fréret S., Fabre-Nys C., Fritzc S., Monget P., Dupont F. and Dupont J. (2010). Ovarian parameters and fertility of dairy cows selected for one QTL located on BTA3. Theriogenology. 75, 1239-1250.
Crabbe B.G., Freeman D.A., Grant B.D., Kennedy P., Whitlatch L. and Mac Rae K. (1992). Testicular feminization syndrome in a mare. J. Am. Vet. Med. Assoc. 200, 1689-1691.
Craig A.M. and Denhardt D.T. (1991). The murine gene encoding secreted phosphoprotein 1 (OPN, osteopontin): promoter structure, activity, and induction in vivo by estrogen and progesterone. Gene. 100, 163-171.
Cushman R.A., Allan M.F., Jones S.A., Rupp G.P. and Echternkamp S.E. (2007). Localization of period 1 mRNA in the ruminant oocyte and investigations of its role in ovarian function. Anim. Reprod. Sci. 99, 93-105.
Dai L., Zhao Z., Zhao R., Xiao S., Jiang H., Yue X., Li X., Gao Y., Liu J. and Zhang J. (2009). Effects of novel single nucleotide polymorphisms of the FSH beta-subunit gene on semen quality and fertility in bulls. Anim. Reprod. Sci. 114, 14-22.
Darwash A.O., Lamming G.E. and Woolliams J.A. (1999). The potential for identifying heritable endocrine parameters associated with fertility in post-partum dairy cows. Anim. Sci. 68, 333-347.
Darwish S.F., Mahmoud K.Gh.M. and Scholkamy T.H. (2009). Preliminary trials for sexing of in vitro produced buffalo embryos using multiplex PCR. Global Veterinaria. 3, 178-182.
Degani G., Jackson K., Goldberg D., Sarfati R. and Avtalion R.R. (2003). Beta FSH, beta LH and growth hormone gene expression in blue gourami (Trichogaster trichopterus, Pallas 1770) during spermatogenesis and male sexual behavior. Zool. Sci. 20, 737-743.
De Roux N., Genin E., Carel J.C., Matsuda F., Chaussain J.L. and Milgrom E. (2003). Hypogonadotropic hypogonadism due to loss of function of the kiss1-derived peptide receptor GPR54. Proc. Natl. Acad. Sci. USA.100, 10972-10976.
Douglas J., Meeren H. K.M., Johnstone L.E., Pfaff D.W., Russell J.A. and Brooks P.J. (1998). Stimulation of expression of the oxytocin gene in rat supraoptic neurons at parturition. Brain Research. 782, 167-174.
Drogemuller C., Hamann H. and Distle O. (2001). Candidate gene markers for litter size in different German pig lines. J. Anim. Sci. 79, 2565-2570.
Druet T., Fritz S., Boussaha M., Ben-Jemaa S., Guillaume F., Derbala D., Zelenika D., Lechner D., Charon C., Boichard D., Gut I.G., Eggen A. and Gautier M. (2008). Fine mapping of quantitative trait loci affecting female fertility in dairy cattle on BTA03 using a dense single-nucleotide polymorphism map. Genetics. 178, 2227-2235.
Ekhlasi-Hundrieser M., Schafer B., Kirchhoff C., Hess O., Bellair S., Muller P. and Topfer-Petersen E. (2005). Structural and molecular characterization of equine sperm-binding fibronectin-II module proteins. Mol. Reprod. Dev. 70, 45-57.
EL-Hanafy A.A. and Salem, H.H. (2009). PCR-RFLP of IGFBP-3 gene in some Egyptian sheep breeds. American-Eurasian J. Agric. Environ. Sci. 5, 82-85.
Ellendorff F., Roth E. and Smidt D. (1970). The influence of FSH, LH and testosterone on the sexual behaviour and testicular function of the boar. J. Reprod. Fertil. 21, 347-352.
Elvin J.A., Clark A.T., Wang P., WolfmanN.M.and Matzuk M.M. (1999). Paracrine actions of growth differentiation factor-9 inthe mammalian ovary. Mol. Endocrinol. 13, 1035-1048.
Esposito G., Jaiswal B.S., Xie F., Krajnc-Franken M.A., Robben T.J., Strik A.M., Kuil C., Philipsen R.L., Van Duin M., Conti M. and Gossen J.A. (2004). Mice deficient for soluble adenylyl cyclase are infertile because of a severe sperm-motility defect. Proc. Natl. Acad. Sci. USA. 101, 2993-2998.
FlintA.P.F. (2006). Dairy cow fertility: an inherited disease. Cattle Pract.14, 29-32.
Fu Q., Zhang M., Qin W.S., Lu Y.Q., Zheng H.Y., Meng B., Lu S.S. and Lu K.H. (2007). Cloning the swamp buffalo SRY gene for embryo sexing with multiplex-nested PCR. Theriogenology. 68, 1211-1218.
Gafar S.I. and FlintA.P.F. (1995). Use of polymerase chain reaction in sexing of red deer(Cervus elaphus) blastocysts. Anim. Biotechnol. 6, 111-116.
Gearing D.P., Thut C.J., Vandenbos T., Gimpel S.D., Delaney, P.B., King J., Price V., Cosman D. and Beckmann M.P. (1991). Leukaemia inhibitory factor receptor is structurally related to the IL-6 signal transducer, gp 130. European Mol. Biol. Organiz. J. 10, 2839-2848.
Geisert R.D. and Yelich J.V. (1997). Regulation of conceptus development and attachment in pigs. J. Reprod. Fertil. (Suppl.52), 133-149.
Geisert R.D., Blair R.M., Pratt T. and Zavy M.T. (1997). Characterization and proteolytic activity of a cathepsin L-like polypeptide in endometrium and uterine flushings of cycling, pregnant and steroid-treated ovariectomized gilts. Reprod. Fertil. Dev. 9, 395-402.
Geisert R.D., Yelich J.V., Pratt T. and Pomp D. (1998). Expression of an inter-α-trypsin inhibitor heavy chain-like protein in the pig endometrium during the oestrous cycle and early pregnancy. J. Reprod. Fertil. 114, 35-43.
Gengler N., DusseldorfT., Wiggans G.R., Wright J.R. and Druet T. (2001). Heterogeneity of (co) variance components for Jerseytype traits. J. Dairy Sci. 84, 1772-1788.
Georges M. (2007). Mapping, fine mapping and molecular dissection of quantitative trait loci in domestic animals. Annu. Rev. Genomics Hum. Genet. 8, 131-162.
Giese A., Jude R., Kuiper H., Piumi F., Schambony A., Guerin G., Distl O., Topfer-Petersen E. and Leeb T. (2002a). Molecular characterization of the equine AEG1 locus. Gene. 292, 65-72.
Giese A., Jude R., Kuiper H., Raudsepp T., Piumi F., Schambony A., Guerin G., Chowdhary B.P., Distl O., Topfer Petersen E. and Leeb T. (2002b). Molecular characterization of the equine testis-specific protein 1 (TPX1) and acidic epididymal glycoprotein 2 (AEG2) genes encoding members of the cysteine-rich secretory protein (CRISP) family. Gene. 299, 101-109.
Giudice L.C. (1999). Genes associated with embryonic attachment and implantation and the role of progesterone. J. Reprod. Med. 44,165-171.
GodinI., Deed R., Cooke J., Zsebo K., Dexter M. and Wylie C.C. (1991). Effects of the steel gene product on mouse primordial germ cells in culture. Nature. 352, 807-809.
Gorlov I.P., Kamat A., Bogatcheva N.V., Jones E., Lamb D.J., Truong A., Bishop C.E., McElreavey K. and Agoulnik A.I. (2002). Mutations of the GREAT gene cause cryptorchidism. Hum. Mol. Genet. 11, 2309-2318.
Guillaume F., Gautier M., Ben Jemaa S., Fritz S., Eggen A., Boichard D. and Druet T. (2007). Refinement of two female fertility QTL using alternative phenotypes in French Holstein dairy cattle. Anim. Genet. 38, 72-74.
Haase B., Schlotterer C., Ekhlasi-Hundrieser M., Kuiper H., Distl O., Topfer-Petersen E. and Leeb T. (2005). Evolution of the sperm adhesin gene family. Gene. 352, 20-29.
Hafez B. and Hafez E. (2000). Reproduction in Farm Animals. 7th Ed. Lea and FebigerphiladelphiausaPp. 41-4 6.
Hamatani T., Carter M.G., Sharov A.A. and Ko M.S.H. (2004). Dynamics of global gene expression changes during mouse preimplantation development. Dev. Cell. 6, 117-131.
Hasegawa T., Sato F., Ishida N., FukushimaY. and Mukoyama H. (2000). Sex determination by simultaneous amplification of equine SRY and amelogenin genes. J. Vet. Med. Sci. 62, 1109-1110.
Hawkins J.R., Taylor A., Berta P., Levilliers J., Van der Auwera B. and Goodfellow P.N. (1992). Mutational analysis of SRY: nonsense and missense mutations in XY sex reversal. Hum. Genet. 88, 471-474.
Hermesch S., Luxford B.G. and Graser H.U. (2000). Genetic parameters for lean meat yield, meat quality, reproduction and feed efficiency traits for Australian pigs 3. Genetic parameters for reproduction traits and genetic correlations with production, carcase and meat quality traits. Livest. Prod. Sci. 65, 261-270.
Hilton D.J. (1992). LIF: lots of interesting functions. Trends Biochem. Sci. 17, 72-76.
Hondo E., Kurohmaru M., SakaiS., Ogawa K. and Hayashi Y. (1995). Prolactin receptor expression in rat spermatogenic cells. Biol. Reprod. 52, 1284-1290.
Howden K.J. (2004). Androgen insensitivity syndrome in a thoroughbred mare (64, XY testicular feminization). Can.Vet. J.45, 501-503.
Hsueh A.J.W., McGee E.A., Hayashi M. and Hsu S.Y. (2000). Hormonal regulation of early follicle development in the rat ovary. Mol. Cell. Endocrinol. 163, 95-100.
Hu Y.A. and Huang Y.F. (2002). A serum marker of spermatogenesis-inhibin B. Natl. J. Androl. 8, 57-60.
HuhtaniemiI., Jiang M., Nilsson C. and Pettersson K. (1999). Mutations and polymorphisms in gonadotropin genes. Mol. Cell. Endocrinol. 25, 89-94.
Ikeobi C.O., Woolliams J.A., Morrice D.R., Windsor D., Burt D.W and Hocking P.M (2002). Quantitative trait loci affecting fatness in the chicken. Poult. Sci. 33, 428-435.
Imboonta N., Rydhmer L. and Tumwasorn S. (2007). Genetic parameters and trends for production and reproduction traits in Thai Landrace sows. Livest. Sci. 111, 70-79.
Ing N.H.and Roberts R.M. (1989). The major progesteronemodulated proteins secreted into the sheep uterus aremembers of the serpin superfamily of serine protease inhibitors. J. Biol. Chem. 264, 3372-3379.
Ivell R. and Hartung S. (2003). The molecular basis of cryptorchidism. Mol. Hum. Reprod. 9, 175-181.
Jeon K., Kima E.Y., Tae J.C., Lee C.H., Lee K.S., Kima Y.O., Jeongd D.K., Cho S.K., Kim J.H., Lee H.Y. , Riu K.Z. , Cho S.G. and Park S.P. (2008). Survivin protein expression in bovine follicular oocytes and their in vitro developmental competence. Anim. Reprod. Sci. 108, 319-333.
Johnson M.H., Lim A., Fernando D. and Day M.L. (2002). Circadian clockwork genes are expressed in the reproductive tract and conceptus of the early pregnant mouse. Reprod. Bio. Med. Online. 4, 140-145.
Jorritsma R., Wensing T., Kruip T.A.M., Vos P.L.A.M. and Noordhuizen J.P.T.M. (2003). Metabolic changes in early lactation and impaired reproductive performance in dairy cows. Vet. Res. 34, 11-26.
Kaewmala K., Uddina M.J., Cinara M.U., Große-Brinkhausa C., Jonasa E., Tesfayea D., Phatsaraa C., Tholena E., Loofta C. and Schellandera K. (2011). Association study and expression analysis of CD9 as candidate gene for boar sperm quality and fertility traits. Anim. Reprod. Sci. (in press).
Kaipia A., Penttila T.L., Shimasaki S., Ling N., Parvinen M. and Toppari J. (1992). Expression of inhibin beta A and beta B, follistatin and activin-A receptor messenger ribonucleic acids in the rat seminiferous epithelium. Endocrinology. 131, 2703-2710.
Kakoi H., Hirota K., Gawahara H., Kurosawa M. and Kuwajima M. (2005). Genetic diagnosis of sex chromosome aberrations in horses based on parentage test by microsatellite DNA and analysis of X- and Y-linked markers. Equine Vet. J. 37, 143-147.
Kandasamy S., Jain A., Kumar R., Agarwal S. K., Joshi P. and Mitra A. (2010). Molecular characterization and expression profile of uterine serpin (SERPINA14) during different reproductive phases in water buffalo (Bubalus bubalis). Anim. Reprod. Sci. 122, 133-141.
Karp A., Ingram D.S. and Issac P.G. (1997). Molecular Tools for Screening Biodiversity: Plant and Animals. 1st Ed., Springer, London, Pp. 528.
Kawahara-Miki R., Tsuda K., Shiwa Y., Arai-Kichise Y., Matsumoto T., Kanesaki Y., Oda S., Ebihara S., Yajima S., Yoshikawa H. and Kono T. (2011). Whole-genome resequencing shows numerous genes with nonsynonymous SNPs in the Japanese native cattle Kuchinoshima-Ushi. BMC Genomics. 12, 103-110.
Kawamura K., Sato N., Fukuda J., Kodama H., Kumagai J. Tanikawa H., Nakamura A., Honda Y., Sato T. and Tanaka T. (2003). Ghrelin inhibits the development of mouse pre-implantation embryos in-vitro. Endocrinology. 144, 2623-2633.
Kennedy T.G., Brown K.D. and VaughanT.J. (1994). Expression of the genes for the epidermal growth factor receptor and its ligands in porcine oviduct and endometrium. Biol. Reprod. 50, 751-756.
Khatib H., Maltecca C., Monson R.L., Schutzkus V. and Rutledge J.J. (2009). Monoallelic maternal expression of STAT5A affects embryonic survival in cattle. B.M.C. Genetics. 10, 13.
Khatib H., Monson R.L., Schutzkus V., Kohl D.M., Rosa G. J. M. and Rutledge J.J. (2008). Mutations in the STAT5A gene are associated with embryonic survival and milk composition in cattle. J. Dairy Sci. 91, 784-793.
Kim G.Y., Besner G.E., Steffen C.L., McCarthy D.W., Downing M.T., Luquette M.H., Abad M.S. and Brigstock D.R. (1995). Purification of heparin-binding EGF-like growth factor from pig uterine flushings and its production by endometrial tissues. Biol. Reprod. 52, 561-571.
Kirkpatrick B.W., Byla B.M. and Gregory K.E. (2000). Mapping quantitative trait loci for bovine ovulation rate. Mamm.Genome. 11, 136-139.
Kirschke H., Kembhavi A.A., Bohely P. and Barrett A.J. (1982). Action of rat liver cathepsin L on collagen and other substrates. Biochem. J. 201, 367-372.
Kissel H., Timokhina I., Hardy M.P., Rothschild G., Tajima Y., Soares V., Angeles M., Whitlow S.R., Manova K. and Besmer P. (2000). Point mutation in kit receptor tyrosine kinase reveals essential roles for kit signaling in spermatogenesis and oogenesis without affecting other kit responses. European Mol. Biol. Organiz. J. 19, 1312-1326.
Klonisch T., Steger K., Kehlen A., Allen W.R., Froehlich C., Kauffold J., Bergmann M. and Hombach-Klonisch S. (2003). INSL3 ligand-receptor system in the equine testis. Biol. Reprod. 68, 1975-1981.
Kobayashi Y., Jimenez-Krassel F., Li Q., YaoJ., Huang R., IrelandJ.J., Coussens P.M. and Smith G.W. (2004). Evidence that cocaine- and amphetamine-regulated transcript is a novel intraovarian regulator of follicular atresia. Endocrinology. 145, 5373-5383.
Krausz C., Forti G. and McElreavey K. (2003). The Y chromosome and male fertility and infertility. Int. J. Androl. 26, 70-75.
Kubien E.M., Pozor M.A. and Tischner M. (1993). Clinical, cytogenetic and endocrine evaluation of a horse with a 65,XXY karyotype. Equine Vet. J. 25, 333-335.
Kumar O.S., Sharma D., Singh D. and Sharma M.K. (2009). CYP19 (cytochrome P450 aromatase) gene polymorphism in murrah buffalo heifers of different fertility performance. Res. Vet. Sci. 86, 427-437.
Kumar S., Gupta T., Kumar N., Dikshit K., Navani N., Jain P. and Nagarajan M. (2006). Genetic variation and relationships among eight Indiariverine buffalo breeds. Mol. Ecol. 15, 593-600.
Lande R. and Thompson R. (1990). Efficiency of marker-assisted selection in the improvement of quantitative traits. Genetics. 24, 743-756.
Layman L.C. (2000). Mutations in the follicle stimulating hormone beta (FSHB) and FSH receptor genes in mice and humans. Semin. Reprod. Med. 18, 5-10.
Lee D.K., Nguyen T., O’Neill G.P., Cheng R., Liu Y., Howard A.D., Coulombe N., Tan C.P., Tang-Nguyen A.T., George S.R. and O’Dowd B.F. (1999). Discovery of a receptor related to the galamin receptors. FEBS. Lett. 446, 103-107.
Leeb T., Sieme H. and Topfer-Petersen E. (2005). Genetic markers for stallion fertility-lessons from humans and mice. Anim. Reprod. Sci. 89, 21-29.
Le Naour F., Rubinstein E., Jasmin C., Prenant M. and Boucheix C. (2000). Severely reduced female fertility in CD9-deficient mice. Science. 287, 319-321.
Leroy J., Opsomer G., Van Soom A., Goovaerts I.G.F. and Bols P. (2008a). Reduced fertility in high-yielding dairy cows: Are the oocyte and embryo in danger? Part I - The importance of negative energy balance and altered corpus luteum function to the reduction of oocyte and embryo quality in high-yielding dairy cows. Reprod. Domest. Anim. 43, 612-622.
Leroy J., Van Soom A., Opsomer G., Goovaerts I.G.F. and Bols P.E.J. (2008b). Reduced fertility in high-yielding dairy cows: Are the oocyte and embryo in danger? Part II - Mechanisms linking nutrition and reduced oocyte and embryo quality in high-yielding dairy cows. Reprod. Domest. Anim. 43, 623-632.
Li M.D., Macdonald G.J., Wise T. and Ford J.J. (1998a). Positive association between expression of follicle-stimulating hormone beta and activin beta B-subunit genes in boars. Biol. Reprod. 59, 978-982.
Li N., Zhoa Y.F., Xiao L., Zang F.J., Chen Y.Z., Dai R.J., Zang J.S., Shen S.Q., Chen Y.F. and Wu C.X. (1998b). Candidate gene analysis for identification of genetic loci controlling litter size in swine. Pp. 183-186 inProc. 6th World Congress on Genetics Applied to Livestock Production, Armidale. 26, 183-186.
Li W., Jaffe R.C. and Verhage H.G. (1992). Immunocytochemical localization and messenger ribonucleic acid levels of a progesterone-dependent endometrial secretory protein (cathepsin L) in the pregnant cat uterus. Biol. Reprod. 47, 21-28.
Lin C.L., Ponsuksili S., Tholen E., Jennen D.G.J., Schellander K. and Wimmers K. (2006). Candidate gene markers for sperm quality and fertility of boar. Anim. Reprod. Sci. 92, 349-363.
Lin S., Miyata S., Weng W., Matsunaga W., IchikawaJ., Furuya K., Nakashima T. and Kiyohara T. (1998). Comparison of the expression of two immediate early gene proteins,FosB and Fos in the rat preoptic area, hypothalamus and brainstemduring pregnancy, parturition and lactation. Neuroscience Research. 32, 333-341.
Linville R.C., Pomp D., Johnson R.K. and Rothschild M.F. (2001). Candidate gene analysis for loci affecting litter size and ovulation rate in swine. J. Anim. Sci. 79, 60-67.
Liska F. (2003). Selected genetic aspects of male infertility what animal models tell us. Folia. Biol. (Praha). 49, 129-141.
Lovercamp K.W., Safranski T.J., Fischer K.A., Manandhar G., Sutovsky M., Herring W. and Sutovsky P. (2007). Arachidonate 15-lipoxygenase and ubiquitin as fertility markers in boars. Theriogenology. 67, 704-718.
Lucy M.C. (2001). Reproductive loss in high-producing dairy cattle: Where will it end? J. Dairy Sci. 84, 1277-1293.
Maeda T., Nishida J. and Nakanishi Y. (1999). Expression pattern, subcellular localization and structure-function relationship of rat Tpx-1, aspermatogenic cell adhesion molecule responsible for association with Sertoli cells. Dev. Growth. Differ. 41, 715-722.
Malhotra N., Singh D. and Sharma M.K. (2007). Cloning, expres-sion and hormonal regulation of steroidogenic acute regulatory protein gene in buffalo ovary. Asian-Aust. J. Anim. Sci. 20, 184-193.
Mannaertz B., Uilenbrock J., Schot P. and De Leeuw R. (1994). Folliculogenesis in hypophysectomized rats after treatment with recombinant human follicle stimulating hormone. Biol. Reprod. 51, 72-81.
Marson E.P., Ferrez J.B.S., Meirelles F.V., Balieiroand J.C.C. and Eler J.P. (2008). Effects of polymorphisms of LHR and FSHR genes on sexual precocity in a Bos taurus x Pos indicus beef composite population. Genet. Mol. Res. 7, 243-251.
Martin L.C., Brinks J.S., Bourdon R.M. and Cundiff L.V. (1992). Genetic effects on beef heifer puberty and subsequent reproduction. J. Anim. Sci. 70, 4006-4017.
Mason R.W., Johnson D.A., Barrett A.J. and Chapman H. (1982). Elastinolytic activity of human cathepsin L. Biochem. J.233, 925-927.
Matzuk M.M. and Lamb D.J. (2002). Genetic dissection of mammalian fertility pathways. Nat. Cell. Biol. 4, 41-49.
McPhaul M.J., Marcelli M., Zoppi S., Wilson C.M., Griffin J.E. and Wilson J.D. (1992). Mutations in the ligand binding domain of the androgen receptor gene cluster in two regions of the gene. J. Clin. Invest. 90, 2097-2101.
Meinhardt A., O’bryan M.K., Mcfarlane J.R., LovelandK.L., Mallidis C., Foulds L.M., Phillips D.J. and De Kretser D.M. (1998). Localization of follistatin in the rat testis. J. Reprod. Fertil. 112, 233-241.
Metcalf D. (1992). Leukemia inhibitory factor-a puzzling polyfunctional regulator. Growth Factors. 7, 169-173.
Meyer K., Hammond K., Parnell P.F., Mackinnon M.J. and Sivarajasingam S. (1990). Estimates of heritability and repeatability for reproductive traits in Australian beef cattle. Prod. Sci. 25, 15-30.
Miki K., Qu W., Goulding E.H., Willis W.D., Bunch D.O., Strader L.F., Perreault S.D., Eddy E.M. and O’Brien D.A. (2004). Glyceraldehyde 3-phosphate dehydrogenase-S, a sperm-specific glycolytic enzyme, is required for sperm motility and male fertility. Proc. Natl. Acad. Sci. USA. 101, 16501-16506.
Miki K., Willis W.D., Brown P.R., Goulding E.H., Fulcher K.D. and Eddy E.M. (2002). Targeted disruption of the Akap4 gene causes defects in sperm flagellum and motility. Dev. Biol. 248, 331-342.
Minj A., Mondal S., Tiwari A.K., Sharma B. and Varshney V.P. (2008). Molecular characterization of follicle stimulating hormone receptor (FSHR) gene in the Indian riverbuffalo (Bubalus bubalis). Gen. Comp. Endocrinol. 158, 147-153.
Miyamoto T., Hasuike S., Yogev L., Maduro M.R., Ishikawa M., Westphal H. and Lamb D.J. (2003). Azoospermia in patients heterozygous for a mutation in SYCP3. Lancet. 362, 1714-1719.
Modric T., Kowalski A.A., Green M.L., Simmen R.C.M. and Simmen F.A. (2000). Pregnancy-dependent expression of leukaemia inhibitory factor (LIF), LIF receptor-β and interleukin-6 (IL-6) messenger ribonucleic acids in the porcine female reproductive tract. Placenta. 21, 345-353.
Moffatt J., Bazer F.W., Hansen P.J., Chun P.W. and Roberts R.M. (1987). Purification, secretion and immunocytochemical local ization of the uterine milk proteins, major progesterone-induced proteins in uterine secretions of the sheep. Biol. Reprod. 36, 419-430.
Moltenia L., Macchia A., De Giovanni Meggiolaroa D., Sironib G., Eniceb F. and Popescuc P. (1999). New cases of XXY constitution in cattle. Anim. Reprod. Sci. 55,107-113.
Monget P. and Bondy C. (2000). Importance of the IGF system in early folliculogenesis. Mol. Cell. Endorcrinol. 163, 89-93.
Moolmuang B. (2004). Development of AFLP markers for a fertility swamp buffalo (Bubalus bubalus). MS Thesis, MahidolUniversity.
Morris C.A. and Cullen N.G. (1994). A note on genetic correlation between pubertal traits in bulls and heifers. Livest. Prod. Sci. 39, 291-297.
Mostafa D.M.M. (2011). Genetic polymorphism of some genes related to reproduction in the river buffalo. MS thesis, Faculty of Science, AinShamsUniversity.
Moura A.A. (2005). Seminal plasma proteins and fertility indexes in the bull: The case for osteopontin. Anim. Reprod. 2, 3-10.
Moura A.A., Chapman D.A., Koc H. and Killian G.J. (2006). Proteins of the cauda epididymal fluid associated with fertility of mature dairy bulls. J. Androl. 27, 534-541.
Muir A.I., Chamberlain L., Elshourbagy N.A., Michalovich D., Moore D.J., Calamari A., Szekeres P.G., Sarau H.M., Chambers J.K., Murdock P., Steplewski K., Shabon U., Miller J.E., Middleton S.E., Darker J.G., Larminie C.G., Wilson S., Bersma D.J., Emson P., Faull R., Philpott K.L. and Harrison D.C. (2001). AXOR12, a novel human G protein-coupled receptor, activated by the peptide kiss-1. J. Biol. Chem. 276, 28969-28975.
Niemann-Sorenson A. and Robertson A. (1961). The association between blood groups and several production characteristics in three Danish cattle breeds. Acta Agric. Scandinavica. 11, 163-196.
Nikpoor P., Mowla S.J., Movahedin M., Ziaee S.A.and Tiraihi T. (2004). CatSper gene expression in postnatal development of mouse testis and in subfertile men with deficient sperm motility. Hum. Reprod. 19, 124-128.
Ohtaki T., Shintani Y., Honda S., Matsumoto H., Hori A., Kanehashi K., Terao Y., Kumano S., Takatsu Y., Masuda Y., Ishibashi Y., Watanabe T., Asada M., Yamada T., Suenaga M., Kitada C., Usuki S., Kurokawa T., Onda H., Nishimur O. and Fujno M. (2001). Metastasis suppressor gene Kiss-1 encodes peptide lignatd of a G-protein. Nature. 411, 613-617.
Omelka R., Bauerova A.M., Mlynek J., Buchova B., Peskovicova D. and Bulla J. (2005). Effect of the oestrogen receptor (ESR) gene on reproductive traits of Large White, White Meaty and Landrace pigs. Czech J. Anim. Sci. 50, 249-253.
PageD.C., Mosher R., Simpson E.M., Fisher E.M., Mardon G., Pollack J., McGillimay B., De la ChapelleA. and Brown L. (1987). The sex determining region of the human Y chromosome encodes a finger protein. Cell. 51, 1091-1104.
Pailhoux E., Cribiu E.P., ParmaP. and Cotinot C. (1995). Molecular analysis of an XY mare with gonadal dysgenesis. Hereditas. 122, 109-112.
Pande A. and Totey S.M. (1998). ZFX and ZFY loci in water buffalo (Bubalus bubalis): Potential for sex identification. Ge-netic Analysis: Biomol. Engin. 14, 85-88.
ParmentierI., Portetelle D., Bertozzi C., Haezebroeck V., Pirad M. and Renaville R. (2001). Marker genes in farm animals. Pp. 47-64 inBiotechnology in Animal Husbandry. R. Renaville and A. Burny (Eds.). Kluwer Academic Publishers. Printed in the Netherlands.
Perks C.M., Peters A.R. and WathesD.C.(1999). Follicular and luteal expression of insulin-like growth factors I and II and the type 1 IGF receptor in the bovine ovary. J. Reprod. Fertil. 116, 157-165.
Phocas F., Bloch C., Chapelle P., Becherel F., Renand G. and Menissier F. (1998). Developing a breeding objective for a French purebred beef cattle selection programme. Livest. Prod. Sci. 57, 49-65.
Pickorz R.P., Gingras S., Hoffmeyer A., Ihle J.N. and Weinstein Y. (2004). Regulation of progesterone levels during pregnancy and parturition by signal transducer and activator of transcription 5 and 20-hydroxysteriod dehydrogenase. Mol. Endocrinol. 19, 431-440.
Prigent S.A.and Lemoine N.R. (1992). The type I (EGF-related) family of growth factor receptors and their ligands. Prog. Growth Fact. Res. 4, 1-24.
Quill T.A., Ren D., Clapham D.E. and Garbers D.L. (2001). A voltage-gated ion channel expressed specifically in spermatozoa. Proc. Natl. Acad. Sci. USA. 98, 12527-12531.
Quill T.A., Sugden S.A., Rossi K.L., Doolittle L.K., Hammer R.E. and Garbers D.L. (2003). Hyperactivated sperm motility driven by CatSper2 is required for fertilization. Proc. Natl. Acad. Sci. USA. 100, 14869-14874.
Raudsepp T., Santani A., Wallner B., Kata S.R., Ren C., Zhang H.B., Womack J.E., Skow L.C. and Chowdhary B.P. (2004). A detailed physical map of the horse Y chromosome. Proc. Natl. Acad. Sci. USA. 101, 9321-9326.
Reicher S., Seroussi E. and Gootwine E. (2010). A mutation in gene CNGA3 is associated with day blindness in sheep. Genomics. 95, 101-104.
Ren D., Navarro B., Perez G., Jackson A.C., Hsu S., Shi Q., Tilly J.L. and Clapham D.E. (2001). A sperm ion channel required for sperm motility and male fertility. Nature. 413, 603-609.
Risbridger G.P., Thomas T., Gurusinghe C.J. and Mcfarlane J.R. (1996). Inhibin-related proteins in rat prostate. J. Endocrinol. 149, 93-99.
Robinson J.A. and Buhr M.M. (2005). Impact of genetic selection on management of boar replacement. Theriogenology. 63, 668-678.
Robinson R.S., Mann G.E., Gadd T.S., Lamming G.E. and WathesD.C.(2000). The expression of the IGF system in the bovine uterus throughout the oestrous cycle and early peregnancy. J. Endocrinol. 165, 231-243.
Rodig S.J., Meraz M.A., White J.M., Lampe P.A., Riley J.K., Arthur C.D., King K.L., Sheehan K.C., Yin L., pennica D., Johnson E.M.J. and Schreiber R.D. (1998). Disruption of the Jakl gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses. Cell. 93, 373-383.
Rothschild M.F. (1996). Genetics and reproduction in the pig. Anim. Reprod. Sci. 42, 143-151.
Royal M.D., Darwash A.O., FlintA.P.E., Webb R., Woolliams J.A. and Lamming G.E. (2000). Declining fertility in dairy cattle: changes in traditional and endocrine parameters of fertility. Anim. Sci. 70, 487-501.
Rozen F., Russo C., Banville D. and Zingg H.H. (1995). Structure, characterization, and expression of the rat oxytocin receptor gene. Proc. Natl. Acad. Sci. USA. 92, 200-204.
Salustri A., Yanagishita M. and Hascall V.C. (1990). Mouse oocytes regulate hyaluronic acid synthesis and mucification by FSH-stimulated cumulus cells. Dev. Biol.138, 26-32.
Savatier P., Lapillonne H., Van Grunsven L.A., Rudkin B.B. and Samarut J. (1996). Withdrawal of differentiation inhibitory activity/leukemia inhibitory factor up-regulates D-type cyclins and cyclin dependent kinase inhibitors in mouse embryonic stem cells. Oncogene. 12, 309-322.
Sayed-Ahmed A., Elmorsy S.E., Rudas P. and Bartha T. (2003). Partial cloning and localization of leptin and leptin receptor in the mammary gland of the Egyptian water buffalo.Domest. Anim. Endocrinol. 25, 303-314.
Schambony A., Gentzel M., Wolfes H., Raida M., NeumannU.and Topfer-Petersen E. (1998b). Equine CRISP-3: primary structure and expression in the male genital tract. Biochim. Biophys. Acta. 1387, 206-216.
Schambony A., Hess O., Gentzel M. and Topfer-Petersen E. (1998a). Expression of CRISP proteins in the male equine genital tract. J. Reprod. Fertil. Suppl. 53, 67-72.
Schoenau W., Porciuncula P.M., Zamberlan G., Mesquita F.S., Vieira V., Oliveira J.F.C. and Goncalves P.B.D. (2005). Association between IGF-IR gene polymorphisms and productive and reproductive traits in Holsteincows. Aq. Bras. Med. Vet. Zootec. 57, 772-776.
Schrooten C., Bovenhuis H., Coppieters W. and Arendonk J.A. (2000). Whole genomes scan to detect quantitative trait loci for conformation and functional traits in dairy cattle. J. Dairy Sci. 83, 795-806.
Seidenspinner T., Bennewitz J. and Thaller G. (2010). Confirming QTL for calving and fertility traits on bovine chromosomes 7 and -10 inGerman Holsteins. Livest. Sci. 129, 237-240.
Seminara S.B., Hayes F.J. and CrowleyW.F.J.R. (1998). Gonadotropin-releasing hormone deficiency in the human (idiopathic hypogonadotropic hypogonadism and Kallmann’s syndrome): pathophysiological and genetic considerations. Endocrinol. Rev. 19, 521-539.
Semple R.K., Achermann J.C., Ellery J., Farooqi I.S., Karet F.E., Stanhope R.G., O’Rahilly S. and Aparicio S.A. (2005). Two novel missense mutations in 9 protein- coupled receptor 54 ina patient with hypogonadotropic hypogonadism. J. Clin. Endocrinol. Metab. 90, 1849-1855.
Settin A., Ismail A., Abo El-Magd M., El-Baz R. and Kazamel A. (2009). Gene polymorphisms of TNF-a2308 (G/A), IL-1021082 (G/A), IL-62174 (G/C) and IL-1Ra (VNTR) in Egyptian cases with type 1 diabetes mellitus. Autoimmunity. 42, 50-55.
ShahN.H.(2007). Prolonged calving intervals in the Nili ravi buffalo. Ital. J. Anim. Sci. 6, 694-696.
Sharifzadeh A. and Doosti A. (2010).Genetic polymorphism at the leptin gene in Iranian Holstein cattle by PCR-RFLP. African J. Microbiol. Res. 4, 1343-1345.
Sharma D., Ghai S. and Singh D. (2009). Different promoter usage for CYP19 gene expression in buffalo ovary and placenta. Gen. Comp. Endocrinol. 162, 319-328.
Silva E., Gaivão M., Leitão S., Amaro A., Lopes da Costaa L. and Mateus L. (2008). Blood COX-2 and PGES gene transcription during the peripartum period of dairy cows with normal puerperium or with uterine infection. Domest. Anim. Endocrinol. 35, 314-323.
Silva J.A.V., Formigoni I.B., Eler J.P. and Ferraz J.B.S. (2006). Genetic relationship among stayability, scrotal circumference and post-weaning weight in Nelore cattle. Livest. Sci. 99, 51-59.
Singh J., Alanda A.S. and Adams G.P. (2000). The reproductive pattern and efficiency of female buffaloes. Anim. Reprod. Sci. 61, 593-604.
Sirard M.A., Richard F., Blondin P. and Robert C. (2006). Contribution of the oocyte to embryo quality. Theriogenology. 65, 126-136.
Snijders S.E.M., Dillon P., O’Callaghan D. and Boland M.P. (2000). Effect of genetic merit, milk yield, body condition and lactation number on in vitro oocyte and development in dairy cows. Theriogenology. 53, 981-989.
Snijders S.E.M., Dillon P.G., O’Farrell K.J., Diskin M., Wylie A.R.G., O’Callaghan D., Rath M. and Boland M.P. (2001). Genetic merit for milk production and reproductive success in dairy cows. Anim. Reprod. Sci. 65, 17-31.
Soller M. (1994). Marker assisted selection: an overview. Anim. Biotech. 5, 193-207.
Soller M. (1998). Marker assisted selection in animal biotechnology. Pp. 387-406 inAgriculture Biotechnology: Books in Soils, Plants and the Environment. A. Altman (Ed). New York Marcel Decker, Inc., NY.
Soller M. and Lipkin E. (2004). Quantitative Trait Loci (QTL). Encyclopedia of Animal Science.
Spicer L.J. and Chamberlain C.S. (1998). Influence of cortisol on insulin-and insulin-like growth factor 1 (IGF-1) induced steroid production and on IGF-1 receptors in cultured bovine granulosa cells and thecal cells. Endocrinology. 9, 153-161.
Spotter A. and Distl O. (2006). Genetic approaches to the improvement of fertility traits in the pig. Vet. J. 172, 234-247.
Stewart C.L. (1994). Leukaemia inhibitory factor and the regulation of pre-implantation development of the mammalian embryo. Mol. Reprod. Dev. 39, 233-238.
Sullivan R. (2004). Male fertility markers, myth or reality. Anim. Reprod. Sci. 82, 83, 341-347.
Tan S. and Nevalainen M.T. (2008). Signal transducer and activator of transcription 5A/B in prostate and breast cancers. Endorcrine-Related Cancer. 15, 367-390.
Tiwari A., Singh D. and Sharma M. K. (2008). Expression of cytochrome P450 aromatase transcripts in buffalo (Bubalus bubalis) ejaculated spermatozoa and its relationship with sperm motility. Domes. Anim. Endocrinol. 34, 238-249.
Tremblay K., Vigneault C., McGraw S., Morin G. and Sirard M. (2006). Identification and characterization of a novel bovine oocyte-specific secreted protein gene. Gene. 375, 44-53.
Turner R.M.O., Casas-Dolz R., Schlingmann K.L. and Hameed S. (2005). Characterization of an A-kinase anchor protein in equine spermatozoa and examination of the effect of semen cooling and cryopreservation on the binding of that protein to the regulatory subunit of protein kinase-A. Am. J. Vet. Res. 66, 1056-1064.
Udby L., Cowland J.B., Johnsen A.H., Sorensen O.E., Borregaard N. and Kjeldsen L. (2002). An ELISA for SGP28/CRISP-3, acysteine-rich secretory protein in human neutrophils, plasma, and exocrine secretions. J. Immunol. Methods. 263, 43-55.
Varani S., Elvin J.A., Yan C., DeMayo J., DeMayo F.J., Horton H.F., Byrne M.C. and Matzuk M.M. (2002). Knockout of pentraxin 3, adownstream target of growth differentiationfactor-9, causes female subfertility. Mol. Endocrinol. 16, 1154-1167.
Vermerris W. (2008). A primer on genetics, genomics and plant breeding. Pp. 47-49 inGenetic Improvement of Bioenergy Crops. Springer, New York.
Vicente J., Pilar M., Castro V., Lavara R. and Moce E. (2004). Study of fertilising capacity of spermatozoa after heterospermic insemination in rabbit using DNA markers. Theriogenology. 61, 1357-1365.
Vignal A., Milan D., San-Cristobal M. and Eggen A. (2002). A review of SNP and other types of molecular markers and their use in animal genetics. Genet. Sel. Evol. 34, 275-305.
Vijayaraghavan S., Goueli S.A., Davey M.P. and Carr D.W. (1997). Protein kinase A-anchoring inhibitor peptides arrest mammalian sperm motility. J. Biol. Chem. 272, 4747-4752.
Vincent A.L., Evans G., Short T.H., Southwood O.I., Plastow G.S., Tuggle C.K. and Rothschild M.F. (1998). The prolactin receptor gene is associated with increased litter size in pigs. Pp. 15-18 inProc. 6th WCGALP, vol. 27, Armidale, Australia, 11-16 January.
Wall E., Brotherstone S., Woolliams J.A., Banos G. and Coffey M.P. (2003). Genetic evaluation of fertility using direct and correlated traits. J. Dairy Sci. 86, 4093-4102.
Waterhouse P., Ranjit S., Xiaojia G., Peeyush K.L. and Denhardt D.T. (1992). Regulated temporal and spatial expression of the calcium-binding proteins calcyclin and OPN (osteopontin) in mouse tissues during pregnancy. Mol. Reprod. Dev. 32, 315-323.
Watson A.J., Westhusin M.E. and Winger Q.A. (1999). IGF paracrine and autocrine interactions between conceptus and oviduct. J. Reprod. Fertil. 54, 303-315.
Wikie P.J., Paszek A.A., Beattie C.W., Alexander L.J., Wheeler M.B. and Schook L.B. (1999). A genomic scan of porcine reproductive traits reveals possible quantitative trait loci (QTLs) for number of corpora lutea. Mamm. Genome.10, 573-578.
Wimmers K., Lin C.L., Tholen E., Jennen D.G., Schellander K. and Ponsuksili S. (2005). Polymorphisms in candidate genes as markers for sperm quality and boar fertility. Anim. Genet. 36, 152-155.
Wu F.C.W., ButlerG.E., Kelnar C.J.H., Huhtaniemi I.and Veldhuis J.D. (1996). Ontogeny of pulsatile gonadotropin releasing hormone secretion from midchildhood, through puberty, to adulthood in the human male: a study using deconvolution analysis and ultrasensitive immunofluorometric assay. J. Clin. Endocrinol. Metab. 81, 1798-1805.
Wu X., Viveiros M.M., Eppig J.J., Bai Y., Fitzpatrick S.L. and Matzuk M.M. (2003). Zygote arrest 1 (Zar1) is a novel maternal-effect gene critical for the oocyte-to-embryo transition. Nat. Genet.33, 187-191.
Xu J., Liao L., Ning G., Yoshida-Komiya H., Deng C. and O’Malley B.W. (2000). The steroid receptor coactivator SRC-3 (p/CIP/RAC3/AIB1/ACTR/TRAM-1) is required for normal growth, puberty, female reproductive function, and mammary gland development. Proc. Natl. Acad. Sci. 97, 6379-6384.
Xu X., Toselli P.A., Russell L.D. and SeldinD.C.(1999). Globozoospermia in mice lacking the casein kinase II alpha-prime catalytic subunit. Nat. Genet.23, 118-121.
Yamada O., Todoroki J., Kizaki K., Takahashi T., Imai K., Patel O.V., Schuler L.A. and Hashizume K. (2002). Expression of prolactin-related protein 1 at the fetomaternal interface during the implantation period in cows. Reproduction. 124, 427-437.
Yan C., Wang P., DeMayo J., DeMayo F.J., Elvin J.A., Carino C., Prasad S.V., Skinner S.S., Dube S.L., Celeste A.J. and Matzuk M.M. (2001).Synergistic roles of bone morphogenetic protein 15 and growth differentiation factor 9 inovarian function. Mol. Endocrinol. 15, 854-866.
Yang W.C., Li S.J., Tang K.Q., Hua G.H., Zhang C.Y., Yu J.N., Han L. and Yang L.G. (2010). Polymorphisms in the 5 upstream region of the FSH receptor gene and their association with superovulation traits in chinese Holsetein cows. Anim. Reprod. Sci. 119, 3-4.
Yao R., Ito C., Natsume Y., Sugitani Y., Yamanaka H., Kuretake S., Yanagida K., Sato A., Toshimori K. and Noda T. (2002). Lack of acrosome formation in mice lacking a Golgi protein, GOPC. Proc. Natl. Acad. Sci. USA. 99, 11211-11216.
Yen P.H. (2004). Putative biological functions of the DAZ family. Int. J. Androl.27, 125-129.
Yuan L., Liu J.G., Hoja M.R., Wilbertz J., Nordqvist K. and Hoog C. (2002). Female germ cell aneuploidy and embryo death in mice lacking the meiosis-specific protein SCP3. Science. 296, 1115-1118.
Yuan L., Liu J.G., Zhao J., Brundell E., Daneholt B. and Hoog C. (2000). The murine SCP3 gene is required for synaptonemal complex assembly, chromosome synapsis, and male fertility. Mol. Cell.5, 73-83.
Zanella E., Lunstra D., Wise T., Kinder J. and Ford J. (1999). Testicular morphology and function in boars differing in concentration of plasma follicle-stimulating hormone. Biol. Reprod. 60, 115-118.
Zhang C., Chen S., Li X., Xu D., Zhang Y. and Yang L. (2009). Genetic and phenotypic parameter estimates for reproduction traits in the Boer dam. Livest. Sci. 125, 60-65.
Zhang X., Jafari N., Barnes R.B., Confino E., Milad M. and Kazer R.R. (2005). Studies of gene expression in human cumulus cells indicate pentraxin 3 as a possible marker for oocyte quality. Fertil. Steril. 83(Suppl 1), 1169-1179.
Zhang Y., Proenca R., Maffei M., Barone M., Leopold L. and Friedman J.M. (1994). Positional cloning of the mouse obese gene and its human homologue. Nature. 372, 425-432.
Zhao Q.B.S. (2002). Genetic markers for genes encoding Pit-1, GHRH-receptor, and IGF-II, and their association with growth and carcass traits in beef cattle. Ph.D. thesis, Ohio State University, USA.