The Effect of Organic Selenium Supplementation on the Broilers' Immune Response
Subject Areas : CamelM.B. Saad 1 , L.R.S. Gertner 2 , L.N. Kuritza 3 , R.M. Hayashi 4 , L. Pickler 5 , E. Santin 6
1 - Laboratory of Microbiology and Avian Pathology, Federal University of Parana, Rua dos Funcionarios, 1540, Juvevê, Curitiba, Parana, Brazil
2 - Laboratory of Microbiology and Avian Pathology, Federal University of Parana, Rua dos Funcionarios, 1540, Juvevê, Curitiba, Parana, Brazil
3 - Laboratory of Microbiology and Avian Pathology, Federal University of Parana, Rua dos Funcionarios, 1540, Juvevê, Curitiba, Parana, Brazil
4 - Laboratory of Microbiology and Avian Pathology, Federal University of Parana, Rua dos Funcionarios, 1540, Juvevê, Curitiba, Parana, Brazil
5 - Laboratory of Microbiology and Avian Pathology, Federal University of Parana, Rua dos Funcionarios, 1540, Juvevê, Curitiba, Parana, Brazil
6 - Laboratory of Microbiology and Avian Pathology, Federal University of Parana, Rua dos Funcionarios, 1540, Juvevê, Curitiba, Parana, Brazil
Keywords: Performance, Broiler, immune system, CD3+ cells, organic selenium,
Abstract :
The aim of this study was to evaluate the effect of organic selenium supplementation on the immune response of broilers vaccinated against coccidiosis, Infection Bursal Disease Virus (IBDV) and Newcastle Diseases Virus (NDV). The study included three treatments (T), T1= control (inclusion of inorganic selenium in a basal diet), T2= basal diet + 0.2 ppm of organic selenium as selenomethionine and selenocysteine, T3= basal diet + 0.4 ppm of organic selenium as selenomethionine and selenocysteine. Birds supplemented with organic selenium showed higher numbers of CD3+cells in duodenum and less severe ileal lesions compared to birds in the control group. Organic selenium supplementationin the diet had no significant, except for 14 to 21 days of age, effect on broiler weight gain.
Anciuti M.A., Rutz F., Silva L.A., Cosenza R.C. and Silva R.G. (2004). Effectof replacement of dietary inorganic by organic selenium (Sel-Plex®) on the performance of broilers. Proc. An. Symp. Biotech. Feed. Ind. 20,14-19.
Arthur J.R., Mckenzie R.C. and Beckett. G.J. (2003). Selenium in the immune system. J. Nutr. 133, 1457-1459.
Barua A. and Yoshimura Y. (2004). Ovarian cell-mediated immune response to Salmonella Enteritidis infection in laying hens (Gallus domesticus). Poult. Sci. 83, 997-1002.
Cunnigham C.H. (1971). Virologia practica. 6th Ed. Zaragoza Acribia.
Daza A., Salado S., Gálvez J.F. and Gutiérrez Barquín M. (2000). Efecto de la suplementación con vitamina E y Selenio sobre el sistema inmune, parámetros hematológicos y parámetros productivos de lechones recién destetados. Departamento del Producción Animal. E.T.S. de Ingenieros Agrónomos. 15,1-2.
Johnson J. and Reid W.M. (1970). Anticoccidial drugs: lesion scoring techniques in battery and floor-pen experiments with chickens. Experim. Parasitol. 28, 30-36.
Karadas F. and Surai P.F. (2004). Interações entre selênio e vitamina E: será que 1+1 é igual a mais 2 Pp. 57-69 in Anais do Simpósio Brasileiro Alltech: Re-imaginando a indústria de alimentação animal. Biotecnologia Nutricional na Indústria de Alimentação Animal.
Kindlein G., Ribeiro A.M.L., Canal C.W. and Vieira M.M. (2007). Feeding different levels of vitamin E and selenium has no effect on serum immunoglobulin Y (IgY) production by layers vaccinated against Escherichia coli and avian encephalomyelitis virus.Ciência. Rural. 37, 1374-1379.
Koutsos E.A. and Klasing K.C. (2001). Interactions between the immune system, nutrition and productivity of animals. Rec. Advan. Anim. Nutr. 21, 173-190.
Leng L., Bobzek R., Kuriková S., Boldizárová K., Grešáková L., Ševcíková Z., Révajová V., Levkutová M. and Levkut M. (2003). Comparative metabolic and immune responses of chickens fed diets containing inorganic selenium and Sel-PlexTM organic selenium. Pp. 131-145 in Proc. Nutritional Biotechnology in the Feed and Food Industry, Alltech’s 19th Ann. Symp. Nottingham University Press, UK.
MaiorkaA., Silva A.V.F., Santin E., Borges S.A., Boleli I.C. and Macari M. (2000). Influência da suplementação de glutamina sobre o desempenho e o desenvolvimento de vilos e criptas do intestino delgado de frangos. Arq. Bras. Méd. Vet. Zoot. 52, 487-490.
Maiorka A., Boleli I.C. and Macari M. (2002). Desenvolvimento e reparo da mucosa intestinal. Pp.172 in Fisiologia aviária aplicada a frangos de corte, M. Macari, Jaboticabal: Funep.
Maiorka A., Santin E. and Dahlke F. (2003). Posthatching water and feed deprivation affect the gastrointestinal tract and intestinal mucosa development of broiler chicks. J. Appl. Poult. Res. 12, 483-492.
Rayman M.G. (2000). The importance of selenium to human health. Lancet. 356, 233-241.
Rutz F., Pan E.A., Xavier G.B. and Anciuti M.A. (2003). Effect of replacement of dietary inorganic by organicselenium (Sel-Plex®) on the performance of broilers. In: Nutritional Biotechnology in the Feed and Food Industries. Pp. 147-161 i Proc. of Alltech’s 19th Ann. Symp. Nottingham University Press, Nottingham, UK.
Rutz F., Anciuti M.A., Rech J.L. and Rossi P. (2004). Impacto dos minerais orgânicos sobre o desempenho animal. Pp. 74-82 in Proc. Anais do Simpósio Brasileiro Alltech: Re-imaginando a indústria de Alimentação Animal. Biotecnologia Nutricional na Indústria de Alimentação Animal. Ed., Andrea Malaguido e Fernando Rutz.
Santin E., Maiorka A., Macari M., Grecco M., Sanchez J.C., Okada T.M. and Myasaka A.M. (2001). Performance and intestinal mucosa development in broiler chickens fed diets containing saccharomyces cerevisiae cell wall. J. Appl. Poult. Res. 10, 236-244.
Surai P.F. (2000). Organic selenium: benefits to animals and humans, a biochemist’s view. In Pp. 205-260 in Proc. Alltech’s 16th Ann Sym. Nottingham University Press, Biotechnology in the Feed Industry. Nottingham, UK.
Surai P.F. (2002) Natural antioxidants in Avian Nutrition and Reproduction. Nottingham University Press, Nottingham.