The Effect of Bovine Lactoferrin and Probiotic on Performance and Health Status of Ghezel Lambs in Preweaning Phase

Subject Areas : Camel

M. Mallaki ¹ , ع. حسینخانی ² , A. Taghizadeh ³ , G. Hamidian ⁴ , H. Paya ⁵

1 - Department of Animal Science, Faculty of Agriculture, University of Tabriz, Tabriz, Iran
2 - گروه علوم دامی - دانشکده کشاورزی - دانشگاه تبریز
3 - Department of Animal Science, Faculty of Agriculture, University of Tabriz, Tabriz, Iran
4 - Department of Basic Science, Faculty of Veterinary, University of Tabriz, Tabriz, Iran
5 - Department of Animal Science, Faculty of Agriculture, University of Tabriz, Tabriz, Iran

Received: 2019-10-01 Accepted : 2019-12-15 Published : 2021-03-01

Keywords: immune system, Probiotic, lactoferrin, Antibacterial Properties, ruminant's neonate,

Abstract :

Due to concern about antibacterial substances in animal nutrition; bioactive components such as lactoferrin and probiotic with health effects, can be used in some species that are more sensitive to pathogens. Thirty six suckling male Ghezel lambs in a completely randomized design employing a 2 × 3 factorial arrangement were used to study the effects of bovine lactoferrin (BLF) and probiotic on performance, blood and immune system parameters in the pre-weaning phase. Experimental treatments were as follow: 1) control (without BLF and probiotic), 2) 1 g/d probiotic, 3) 0.25 g/d BLF, 4) 0.25 g/d BLF and 1 g/d probiotic, 5) 0.5 g/d BLF, 6) 0.5 g/d BLF and 1 g/d probiotic. Final body weight, weight gain, feed intake and feed efficiency (FE) were significantly affected by the treatments (p <0.05). Diet supplementation with BLF plus probiotic improved performance parameters more than diets without probiotics; however there is no difference between BLF levels. No significant differences was found among health status indices except medicated days (p <0.05). Moreover, no differences were observed in erythrocyte, hematocrit, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC). Conversly hemoglobin, white blood cells (WBC), segmented neutrophil and lymphocyte percentag were significantly affected by the treatments (p <0.05). Additionally experimental treatments significantly changed plasma concentrations of Fe, non-esterified fatty acids (NEFA) and glucose (p <0.05). According to results of present experiment, it seems that BLF plus probiotic can have synergisc effect on performance and heath status of Ghezel lamb breed in preweaning phase.

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