Investing the relation between different types of acute appendicitis with the number of white blood cell and C-reactive protein level

Subject Areas :

Forough Khaleghi nezhad ¹ , Seyed Mojtaba Taheri ^{2 *} , Ladan Shahba ³

1 - Faculty of Medicine, Ke.C., Islamic Azad University, Kerman, Iran
2 - Faculty of Medicine, Ke.C., Islamic Azad University, Kerman, Iran
3 - Faculty of Medicine, Ke.C., Islamic Azad University, Kerman, Iran

Received: 2025-07-16 Accepted : 2025-10-12 Published : 2025-09-13

Keywords: acute appendicitis, White Blood Cell, C-reactive Protein,

Abstract :

Acute appendicitis is one of the surgical emergencies that has many differential diagnoses. The accuracy of clinical diagnosis in acute appendicitis is between 76% and 92%, and the error rate in acute appendicitis diagnosis is 9.3% in men and 23.2% in women. Therefore, it is important to use paraclinical help to diagnose and cure this disease, and prevent its complications. Considering the importance of diagnosis, we decided to determine the relationship between acute appendicitis and WBC count and CRP level in patients admitted to Payambar Azam Hospital in Kerman in 2022. All patients without age limitation visited Payambar Azam Hospital in Kerman in 2022 with abdominal pain suspected to be appendicitis were included in the study. All patient information, including age, gender, neutrophils, white blood cell count, C-reactive protein level, were extracted from the files and recorded in the data collection form. After data collection, SPSS version 20 software was used for analysis. In this study, 169 patients were examined, of which 82 (48.5%) were women and 87 (51.5%) were men. The average age of the patients was 24.28 ± 14.62. According to the type of appendicitis, 86 people (50.9%) were acute, 51 people (30.2%) had purulent appendicitis, and 32 people (18.9%) had gangrene. The frequency of positive C-reactive protein, White Blood Cells above 10000, and neutrophils was statistically significant according to the type of appendicitis. Due to the fact that there is a possibility that many diseases that cause symptoms like acute appendicitis will mistakenly lead to appendectomy, the results of our study showed that by measuring CRP and counting White Blood Cells along with clinical examination, appendectomy can be performed.

 

Keywords: Acute appendicitis, C-reactive Protein, White Blood Cell.

 

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