Toxoplasmosis among Patients with Cancers and Blood Disorders in Iran: Serological Evaluation, Risk Factors and Comparison with Healthy Individuals

Subject Areas : Journal of Chemical Health Risks

Muhammad I Getso ¹ (Department of Medical Microbiology and Parasitology, College of Health Sciences, Bayero University Kano PMB 3011 Kano-Nigeria)
Vahid Raissi ² (Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran)
Maryam Fasihi Karami ³ (Department of Medical Parasitology and Mycology, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran)
Gita Alizadeh ⁴ (Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran)
Mohammad Zareie ⁵ (Department of Basic Sciences of Veterinary Medicine, Kazerun branch, Islamic Azad University, Kazerun, Iran)
Zahra Babaei Samani ⁶ (DVM student at faculty of Veterinary Medicine, Shahrekord university, shahrekord, Iran)
Fatemeh bayat ⁷ (Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran)
Omid Raiesi ⁸ (Department of Medical Parasitology and Mycology, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran)
Soodabeh Etemadi ⁹ (Infectious Diseases and Tropical Medicine Research Center, Resistant Tuberculosis Institute, Zahedan University of Medical Sciences, Zahedan, Iran|Department of Medical Parasitology and Mycology, Faculty of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran)

Received: 2021-01-04 Accepted : 2021-03-25 Published : 2021-09-01

Keywords: Iran, cancer, Epidemiology, Toxoplasmosis, Blood disorders,

Abstract :

Toxoplasma gondii is an obligate intracellular parasite that causes toxoplasmosis in humans and warm-blooded animals. In this study, we explored the risk factors and seroprevalence of Toxoplasma infection among cancer patients and patients with blood cell disorders in Iran. We collected serum samples from each participant include 600 clinically healthy individuals, 127 patients with different types of cancer, 294 patients with red blood cell disorders, and 101 patients with white blood cell disorders and tested for anti-Toxoplasma antibodies (IgG and IgM) using an Enzyme-Linked Immunosorbent Assay kits and analyzed the results statistically.Out of the 1122 participants ,seroprevalence of Toxoplasmosis among all patients with different disorders , patients with white blood cell disorders, patients with red blood cell disorders and patients with different types of cancer 9.97% , 17.82%, 11.57% and 7.09% were reported respectiveiy.Awareness campaign to educate blood cell disorders patients regarding contact with pets is salient to the reduction of the Toxoplasma burden. In addition, it is pertinent to screen patients with cancers to rule out Toxoplasma infections.

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