Contents of Aerial Parts of Salvia leriifolia Benth

Subject Areas : Journal of Chemical Health Risks

Zahra Hosseinpoor Mohsen Abadi ¹ , Behnam Mahdavi ² , Esmaeil Rezaei-Seresht ³

1 - Department of Chemistry, Hakim Sabzevari University, Sabzevar, Iran
2 - Department of Chemistry, Hakim Sabzevari University, Sabzevar, Iran
3 - Department of Chemistry, Hakim Sabzevari University, Sabzevar, Iran

Received: 2016-06-06 Accepted : 2018-10-29 Published : 2016-06-06

Keywords: Antimicrobial Activity, Antioxidant Activity, Radical scavenging activity, Total Phenolic Content, Salvia Leriifolia, Total flavonoid content, Ferrous ion chelating,

Abstract :

In the present study, we have reported the total phenolic content, total flavonoid content, antioxidant and antimicrobial activity of aerial parts of Salvia leriifolia extracts and fractions. Methanolic, n-hexane, chloroform, and ethyl acetate extracts were screened to analysis their antioxidant activities by four complementary test systems, namely DPPH free radical scavenging activity (RSA), total phenolic content (TPC), total flavonoid content (TFC), and ferrous ion cheating (FIC). In most cases the leaf extracts and ethyl acetate fraction had more activity. The methanolic extracts of leaf and flower showed considerable antimicrobial activity using disc diffusion method against Escherichia coli, Streptococcus pneumonia, Acinetobacter, Serratia, Pseudomonas aeruginosa. The extracts showed the highest activity against P. aeruginosa and K. pneumonia.

References:

1. Lima C.F., Andrade P.B., Seabra R.M., Fernandes-Ferreira M., Pereira-Wilson C., 2005. The drinking of a Salvia officinalis infusion improves liver antioxidant status in mice and rats. J Ethnopharmacol. 97(2),383-389.
2. González A.G., Abad T., Jiménez I.A., et al., 1989. A first study of antibacterial activity of diterpenes isolated from some Salvia species (Lamiaceae). Biochem. Syst Ecol. 17(4), 293-296.
3. Hosseinzadeh H., Haddadkhodaparast M.H., Arash A.R., 2003. Antinociceptive, antiinïÂ‌‚ammatory and acute toxicity effects of Salvia leriifolia Benth. seed extract in mice and rats. Phytother Res. 17(4), 422-425.
4. Hernández-Pérez M., Rabanal R.M., de la Torre M.C., Rodríguez B., 1995. anti-inflammatory, antipyretic and haematological effects of aethiopinone, an o-naphthoquinone diterpenoid from Salvia aethiopis roots and two hemisynthetic derivatives. Planta Med. 61(6), 505-509.
5. A Alarconââ‚‌Aguilar F., Romanââ‚‌Ramos R., Floresââ‚‌Saenz J., Aguirreââ‚‌Garcia F., 2002. Investigation on the hypoglycaemic effects of extracts of four Mexican medicinal plants in normal and Alloxanââ‚‌diabetic mice. Phytother Res. 16(4), 383-386.
6. Liu J., Shen H.M., Ong C.N., 2000. Salvia miltiorrhiza inhibits cell growth and induces apoptosis in human hepatoma HepG 2 cells. Cancer Lett. 153(1), 85-93.
7. Foster S., 2012. Tyler's honest herbal: a sensible guide to the use of herbs and related remedies: Routledge.
8. Fawole O., Amoo S., Ndhlala A., Light M., Finnie J., Van Staden J., 2010. Anti-inflammatory, anticholinesterase, antioxidant and phytochemical properties of medicinal plants used for pain-related ailments in South Africa. J Ethnopharmacol. 127(2), 235-241.
9. Hosseinzadeh H., Arabsanavi J., 2001. Anticovulsant effect of Salvia leriifolia Benth. Seed and leaf extracts in mice. Iran J Med Sci. 3, 163-170.
10. Hosseinzadeh H., Haddadkhodaparast M., Hosseini E., 2000. Anti-ulcer effect of Salvia leriitolia BENTH. leaf extracts in mice. Pharm Pharmacol Lett. 10(2), 63-64.
11. Hosseinzadeh H., Haddadkhodaparast M., Shokoohizadeh H., 1998. Antihyperglycemic effect of Salvia leriifolia Benth. leaf and seed extract in mice. Iran J Med Sci. 23, 74-80.
12. Hosseinzadeh H., Lary P., 2000. Effect of Salvia leriifolia leaf extract on morphine dependence in mice. Phytother Res. 14(5), 384-387.
13. Kennedy D.ÂÂ‌O., Scholey A.B., 2006. The psychopharmacology of European herbs with cognition-enhancing properties. Curr Pharm Des. 12-(35), 4613-4623.
14. Loizzo M.ÂÂ‌R., Menichini F., Tundis R., Bonesi M., Nadjafi F., Saab A.ÂÂ‌M., Frega N.ÂÂ‌G., Menichini F., 2010. Comparative chemical composition and antiproliferative activity of aerial parts of Salvia leriifolia Benth. and Salvia acetabulosa L. essential oils against human tumor cell in vitro models. J Med Food. 13(1), 62-69.
15. Loizzo M.ÂÂ‌R., Menichini F., Tundis R., Bonesi M., Conforti F., Nadjafi F., Statti G.ÂÂ‌A., Frega N.ÂÂ‌G., Menichini F., 2009. In vitro biological activity of Salvia leriifolia Benth essential oil relevant to the treatment of Alzheimer's disease. J Oleo Sci. 58ÂÂ‌(8), 443-446.
16. Loizzo M.ÂÂ‌R., Tundis R., Conforti F., Menichini F., Bonesi M., Nadjafi F., Frega N.ÂÂ‌G., Menichini F., 2010 Salvia leriifolia Benth (Lamiaceae) extract demonstrates in vitro antioxidant properties and cholinesterase inhibitory activity. Nutr Res. 30ÂÂ‌(12), 823-830.
17. Kolak U., HacibekÄ°roglu I., Öztürk M., Özgökçe F., Topçu G., Ulubelen A., 2009. Antioxidant and anticholinesterase constituents of Salvia poculata. Turk J Chem. 33ÂÂ‌(6), 813-823.
18. Kumaran A., 2006. Antioxidant and free radical scavenging activity of an aqueous extract of Coleus aromaticus. Food Chem. 97ÂÂ‌(1), 109-114.
19. Prior R.L., Cao G., 2000. Antioxidant phytochemicals in fruits and vegetables: diet and health implications. Hort Sci. 35(4), 588-592.
20. Race S., 2009. Antioxidants: The truth about BHA, BHT, TBHQ and other antioxidants used as food additives. Part. 1, 6-11.
21. Moure A., Cruz J.ÂÂ‌M., Franco D., Domı́nguez J.ÂÂ‌M., Sineiro J., Domı́nguez H., Núñez M.ÂÂ‌A.ÂÂ‌J., Parajó J.ÂÂ‌C., 2001. Natural antioxidants from residual sources. Food Chem. 72ÂÂ‌(2), 145-171.
22. Mahdavi B., Yaacob W., Din L.ÂÂ‌B., Jahangirian H., 2013. Antioxidant Activity of Consecutive Extracts of the Base, Stem and Leaves of Etlingera brevilabrum. Asian J Chem. 25ÂÂ‌(7), 3937-3941.
23. Liu X., Ardo S., Bunning M., Parry J., Zhou K., Stushnoff C., Stoniker F., Yu L., Kendall P., 2007. Total phenolic content and DPPH radical scavenging activity of lettuce (Lactuca sativa L.) grown in Colorado. Food Sci Technol. 40ÂÂ‌(3), 552-557.
24. Quettier-Deleu C., Gressier B., Vasseur J., Dine T., Brunet C., Luyckx M., Cazin M., Cazin J.ÂÂ‌C., Bailleul F., Trotin F., 2000. Phenolic compounds and antioxidant activities of buckwheat (Fagopyrum esculentum Moench) hulls and flour. J Ethnopharmacology. 72ÂÂ‌(1), 35-42.
25. Karagözler A.ÂÂ‌A., ErdaÄŸ B., Emek Y.ÂÂ‌Ç., Uygun D.-A., 2008. Antioxidant activity and proline content of leaf extracts from Dorystoechas hastata. Food Chem. 111(2), 400-407.
26. Yen G.ÂÂ‌C., Chen H.ÂÂ‌Y., 1995. Antioxidant activity of various tea extracts in relation to their antimutagenicity. J Agric Food Chem. 43ÂÂ‌(1), 27-32.
27. Chan E., Lim Y.ÂÂ‌Y., Ling S.ÂÂ‌K., Tan S.ÂÂ‌P., Lim K., Khoo M., 2009. Caffeoylquinic acids from leaves of Etlingera speciesÂÂ‌(Zingiberaceae). Food Sci. Technol. 42ÂÂ‌(5), 1026-1030.
28. Singh N., Rajini P., 2004. Free radical scavenging activity of an aqueous extract of potato peel. Food Chem. 85(4), 611-616.
29. CLSI., 2012. Performance Standards for Antimicrobial Disk Susceptibility Tests. CLSI. 32, M02-A11.
30. Mahdavi B., Yaacob W., Din L. B., Nazlina I., 2012. Antimicrobial activity of consecutive extracts of Etlingera brevilabrum. Sains Malays. 41(10), 1233-1237.
31. Chan E., Lim Y., Omar M., 2007. Antioxidant and antibacterial activity of leaves of Etlingera species (Zingiberaceae) in Peninsular Malaysia. Food Chem. 104(4), 1586-1593.
32. Tosun M., Ercisli S., Sengul M., Ozer H., Polat T., Ozturk E., 2009. Antioxidant properties and total phenolic content of eight Salvia species from Turkey. Biol Res. 42(2), 175-181.
33. Bahadori M., Mirzaei M., 2015. Cytotoxicity, antioxidant activity, total flavonoid and phenolic contents of Salvia urmiensis Bunge and Salvia hydrangea DC. ex Benth. Res J Pharm. 2(2), 27-32.
34. Koşar M., Göger F., Can Başer K.H., 2008. In vitro antioxidant properties and phenolic composition of Salvia virgata Jacq. from Turkey. J Agric Food Chem. 56(7), 2369-74.
35. Öğütçü H., Sökmen A., Sökmen M., Polissiou M., Serkedjieva J., Daferera D., et al. 2008. Bioactivities of the various extracts and essential oils of Salvia limbata CA Mey. and Salvia sclarea L. Turk J Biol. 32(3), 181-92.
36. Vishwakarma S., Singh P., Shukla M., Singh U., Singh R., 2013. Antioxidant Activities of Some Tuberous Plant Leaves. Int J Pharm Sci Rev Res. 20(1), 28.
37. Kumar S., Pandey A.K., 2013. Chemistry and biological activities of flavonoids: an overview. Scientific World J. 29;2013:162750. doi: 10.1155/2013/162750.
38. Hamrouni-Sellami I., Rahali F.Z., Rebey I.B., Bourgou S., Limam F., Marzouk B., 2013. Total phenolics, flavonoids, and antioxidant activity of sage (Salvia officinalis L.) plants as affected by different drying methods. Food Bioprocess Tech. 6(3), 806-817.
39. Mistry S.S., Shah S.K., 2014. Anti-oxidant activity of methanolic extract of Ficus religiosa linn bark by using DPPH ((1, 1-Diphenyl-2-Picrylhydrazyl). Int J Phyto Pharm. 4(2), 57-58.
40. Bejeli M., Rowshan V., Zakerin A., 2012. Comparison of total phenolic content and antioxidant activity of five Salvia species by FRAP and DPPH assay. Int J Pharm Sci. 4, 572-575.
41. Tepe B., Sokmen M., Akpulat H.A., Sokmen A., 2006. Screening of the antioxidant potentials of six Salvia species from Turkey. Food Chem. 95(2), 200-204.
42. Amessis-Ouchemoukh N., Madani K., Falé P.L., Serralheiro M.L., Araújo M.E.M., 2014. Antioxidant capacity and phenolic contents of some Mediterranean medicinal plants and their potential role in the inhibition of cyclooxygenase-1 and acetylcholinesterase activities. Ind Crop Prod. 53, 6-15.
43. Zhao G.R., Xiang Z.J., Ye T.X., Yuan Y.J., Guo Z.X., 2006. Antioxidant activities of Salvia miltiorrhiza and Panax notoginseng. Food Chem. 99(4), 767-774.
44. Oktay M., 2004. Evaluation of the antioxidant and antimicrobial activities of clary sage (Salvia sclarea L.). Turk J Agric For. 28, 25-33.
45. Walter M., Marchesan E., 2011. Phenolic compounds and antioxidant activity of rice. Braz Arch Biol Technol. 54(2), 371-377.
46. Lu Y., Foo L.Y., 2001. Salvianolic acid L, a potent phenolic antioxidant from Salvia officinalis. Tetrahedron Lett. 42(46), 8223-8225.
47. Madsen H.L., Bertelsen G., 1995. Spices as antioxidants. Trends Food Sci Technol. 6(8), 271-277.
48. Božin B., Lakić N., Čonić B.S., Kladar N., Orčić D., Mimica-Dukić N., 2012. Antioxidant and antimicrobial properties of a new chemotype of woodland sage (Salvia nemorosa L. subsp. nemorosa, Lamiaceae) essential oil. Biol Serb. 34(1-2).
49. Tenore G.C., Ciampaglia R., Arnold N.A., Piozzi F., Napolitano F., Rigano D., 2011. Antimicrobial and antioxidant properties of the essential oil of Salvia lanigera from Cyprus. Food Chem Toxicol. 49(1), 238-243.
50. Firuzi O., Miri R., Asadollahi M., Eslami S., Jassbi A.R., 2013. Cytotoxic, antioxidant and antimicrobial activities and phenolic contents of eleven salvia species from Iran. Iran J Pharm Res. 12(4), 801.