Effects of Dietary Organic Selenium Supplementation on Performance and Antioxidant Enzymes of Broilers under Heat Stress Conditions: A Meta-Analysis

Subject Areas : Camel

F. Tavakolinasab ¹ , M. Hashemi ²

1 - Department of Animal Science, Faculty of Agriculture, Lorestan University, Khorram-Abad, Iran
2 - Department of Animal Science, Faculty of Agriculture, Lorestan University, Khorram-Abad, Iran

Received: 2023-03-18 Accepted : 2023-05-16 Published : 2023-09-01

Keywords: performance, broiler chickens, heat stress, Antioxidant enzymes,

Abstract :

Heat stress is a major cause of growth retardation and one of the most significant stressors that affect poultry, especially in hot parts of the world. This meta-analysis aimed to evaluate the effect of organic selenium supplementation on antioxidant enzymes and the performance of broiler chickens in heat-stress conditions. From 2003 to 2022, the Scopus, PubMed, Web of Science, and Google Scholar databases were searched. A total of 49, 43, 48, 19, and 27 trials were included to evaluate organic Se effects on feed intake (FI), average daily gain (ADG), feed conversion ratio (FCR), superoxide dismutase (SOD), and glutathione peroxidase (GPX) respectively. The use of organic Se supplementation had no significant effect on ADG (SMD=-0.009, 95% CI -0.105 to +0.086, I2=67.28, P=0.85), FI (SMD=-0.092, 95% CI -0.392 to +0.208, I2=58.53, P=0.548) and FCR (SMD=0.003, 95% CI -0.006 to +0.013, I2=62.89, P=0.47) in the pooled standardized mean difference random effect model. A low concentration of GPX was found in the control group (P=0.000, I2=86.32) in comparison to organic Se supplemented broilers. On the other hand, when the random model was applied to GPX studies, there was much heterogeneity. The standard mean differences of SOD were significantly higher (P<0.041, 95 CI 0.000 to +0.006, I2=0.71) in the treatment receiving Se supplementation. In conclusion, this meta-analysis shows that adding organic Se did not significantly affect on performance, but significantly increased the concentration of SOD and GPX in broilers under heat stress.

References:

Ahmad H., Tian J., Wang J., Khan M.A., Wang Y., Zhang L. and Wang T. (2012). Effects of dietary sodium selenite and selenium yeast on antioxidant enzyme activities and oxidative stability of chicken breast meat. J. Agric. Food Chem. 60, 29-35.

Aljuobori A., Zulkifli I., Soleimani A.F., Abdullah N., Liang J.B. and Mujahid A. (2016). Higher inclusion rate of canola meal under high ambient temperature for broiler chickens. Poult. Sci. 95, 1326-1331.

Amizar R., Suharti S., Jakaria B. and Mutia R. (2017). The expression of heat shock protein 70 gene with organic selenium supplementation and its effect on productivity of broilers in tropical environment. J. Indonesian Trop. Anim. Agric. 42(4), 279-287.

Appuhamy J.A., Strathe A.B., Jayasundara S., Wagner-Riddle C., Dijkstra J., France J. and Kebreab E. (2013). Anti-methanogenic effects of monensin in dairy and beef cattle: A meta-analysis. J. Dairy Sci. 96, 5161-5173.

Attia Y.A. and Hassan S.S. (2017). Broiler tolerance to heat stress at var­ious dietary protein/energy levels. European Poult. Sci. 81, 1-15.

Attia Y.A., Abdalah A.A., Zeweil H.S., Bovera F., El-Din A.T. and Araft M.A. )2010(. Effect of inorganic or organic selenium supplementation on productive performance, egg quality and some physiolog­ical traits of dual-purpose breeding hens. Czech J. Anim. Sci. 55, 505-519.

Azad M.A.K., Kikusato M., Maekawa T., Shirakawa H. and Toyomizu M. (2010). Metabolic characteristics and oxidative damage to skeletal muscle in broiler chickens exposed to chronic heat stress. Comp. Biochem. Physiol. A Mol. Integr. Physiol. 155, 401-406.

Begg C.B. and Mazumdar M. (1994). Operating characteristics of a rank correlation test for publication bias. Biometrics. 50, 1088-1101.

Bermingham E.N., Hesketh J.E., Sinclair B.R., Koolaard J.P. and Roy N.C. (2014). Selenium-enriched foods are more effective at increasing glutathione peroxidase (GPx) activity compared with selenomethionine: A meta-analysis. Nutrients. 6(10), 4002- 4031.

Boostani A., Sadeghi A.A., Mousavi S.N., Chamani M. and Kashan N. (2015). Effects of organic, inorganic, and nano-Se on growth performance, antioxidant capacity, cellular and humoral immune responses in broiler chickens exposed to oxidative stress. Livest. Sci. 178, 330-336.

Borenstein M., Hedges L.V., Higgins J.P.T. and Rothstein H.R. (2009). Computing Effect Sizes for Meta-analysis. John Wiley and Sons, Ltd., Chichester, United Kingdom.

Calik A., Emami N.K., White M.B., Walsh M.C., Romero L.F. and Dalloul R.A. (2022). Influence of dietary vitamin E and selenium supplementation on broilers subjected to heat stress, Part I: Growth performance, body composition and intestinal nutrient transporters. Poult. Sci. 101, 1-10.

Celi P., Selle P.H. and Cowieson A.J. (2015). Effects of organic selenium supplementation on growth performance, nutrient utilization, oxidative stress and selenium tissue concentrations in broiler chickens. Anim. Prod. Sci. 54(7), 966-971.

Chen S., Xue Y., Shen Y., Ju H., Zhang X., Liu J. and Wang Y. (2022). Effects of different selenium sources on duodenum and jejunum tight junction network and growth performance of broilers in a model of fluorine-induced chronic oxidative stress. Poult. Sci. 101, 1-12.

Dai S.F., Wang L.K., Wen A.Y., Wang L.X. and Jin G.M. (2009). Dietary glutamine supplementation improves growth performance, meat quality and colour stability of broilers under heat stress. British Poult. Sci. 50, 333-340.

Dlouha G., Sevcikova S., Dokoupilova A., Zita L., Heindl J. and Skrivan M. (2008). Effect of dietary selenium sources on growth performance, breast muscle selenium, glutathione peroxidase activity and oxidative stability in broilers. Czech J. Anim. Sci. 53(6), 265-269.

Duval S. and Tweedie R. (2000). Trim and fill: A simple funnelplot- based method of testing and adjusting for publication bias in meta-analysis. Biometrics. 56, 455-463.

Egger M., Davey Smith G., Schneider M. and Minder C. (1997). Bias in meta-analysis detected by a simple, graphical test. British Med. J. 315, 629-634.

Fan C., YC B. and Chen D. (2009). Effects of different sources and levels of selenium on performance, thyroid function, and antioxidant status in stressed broiler chickens. Int. J. Poult. Sci. 8(6), 583-587.

Gao X., Xing H., Li S., Li J., Ying T. and Xu S. (2012). Selenium regulates gene expression of selenoprotein W in chicken gastrointestinal tract. Biol. Trace Elem. Res. 145, 181188.

Goo D., Kim J.H., Park G.H., Delos-Reyes J.B. and Kil D.Y. (2019). Effect of heat stress and stocking density on growth performance, breast meat quality and intestinal barrier function in broiler chickens. Animals. 9, 107-210.

Göçmen R., Yazgan O. and Cufadar Y. (2016). Effect of different organic and inorganic selenium levels on performance, selenium concentrations of some tissues, glutathione peroxidase enzyme activity and meat quality in broilers. J. Anim. Plant Sci. 26(4), 916-923.

Guillin O.M., Vindry C., Ohlmann T. and Chavatte L. (2019). Selenium, selenoproteins and viral infection. Nutrients. 11, 2101.

Gul F., Ahmad B., Afzal S., Ullah A., Khan S., Aman K., Khan M.T., Hadi F., Kiran K., Zahra M., Maqbool T., Mohsin U., Nadeem T., Javed M.A., Ali Q. and Ahmad L. (2022). Comparative analysis of various sources of selenium on the growth performance and antioxidant status in broilers under heat stress. Brazilian J. Biol. 83, 1-10.

Habibian M., Sadeghi G., Ghazi S. and Moeini M.M. (2015). Selenium as a feed supplement for heat-stressed poultry: A review. Biol Trace Elem. Res. 165, 183-193.

Han F., Chen D., Yu B. and Luo W. (2009). Effects of different selenium sources and levels on serum biochemical parameters and tissue selenium retention in rats. Front. Agric. China. 3, 1-9.

Harsini S., Habibian M., Moeini M.M. and Abdolmohammadi A.R. (2012). Effects of dietary selenium, vitamin E, and their combination on growth, serum metabolites, and antioxidant defense system in skeletal muscle of broilers under heat stress. Biol Trace Elem. Res. 148, 322-330.

Higgins J.P.T. and Thompson S.G. (2002). Quantifying heterogeneity in a meta-analysis. Stat. Med. 21, 1539-1558.

Hosseini-Vashan S., Golian A. and Yaghobfar A. (2016). Growth, im­mune, antioxidant, and bone responses of heat stress-exposed broilers fed diets supplemented with tomato pomace. Int. J. Biometeorol. 60, 1183-1192.

Hua S., Zhao L., Xu Z.J., De Marco M., Briens M., Yan X.H. and Sun L.H. (2021). Hydroxy-selenomethionine improves the selenium status and helps to maintain broiler performances under a high stocking density and heat stress conditions through a better redox and immune response. Antioxidants. 10, 1542-1553.

Hu C., Li Y., Xiong L., Zhang H., Song J. and Xia M.S. (2012). Comparative effects of nano elemental selenium and sodium selenite on selenium retention in broiler chickens. Anim. Feed Sci. Technol. 177(3), 204-210.

Ibrahim D., Kijhawy A.T.Y., Khater S.I., Arisha A.H., Mohammed H.A., Abdelazizi A.S., Abd-El-Rahman G.I. and Elabbasy M.T. (2019). Effect of dietary modulation of selenium form and level on performance, tissue retention, quality of frozen stored meat and gene expression of antioxidant status in ross broiler chickens. Animals. 9, 342-351.

Kamel Z.M. and Edens F.W. (2003). Influence of selenium sources on age-related and mild heat stress related changes of blood and liver glutathione redox cycle in broiler chickens (Gallus domesticus). Comp. Biochem Phys. A. 136, 921-934.

Khajali F., Raei A., Aghaei A. and Qujeq D. (2010). Evaluation of dietary organic selenium supplement of different dietary protein concentrations on growth performance, body composition and antioxidative status of broilers reared under heat stress. Asian-Australasian J. Anim. Sci. 23(4), 501-507.

Khan Z.A., Khan I.U., Afzal Z., Khan S., Khan M.A., Hossain F.M.A., Khan R.U., Huang K. and Liu R. (2020). Effects of selenium-enriched probiotics on lameness and growth improvement in broiler chickens under heat stress condition. Acta Vet. Eurasia. 47, 19-28.

Kuczynski T. (2002). The application of poultry behavior responses on heat stress to improve heating and ventilation system efficiency. Electr. J. Pol. Agric. Univ. 5, 1-11.

Kuricova S., Boldizarova K., Gresakova Ľ., Bobcek R., Levkut M. and Leng Ľ. (2003). Chicken selenium status when fed a diet supplemented with Se-yeast. Acta Vet. Brno. 72(3), 339-346.

Lara L.J. and Rostagno M.H. (2013). Impact of heat stress on poultry production. Animals. 3, 356-369.

Lean I.J., Rabiee A.R., Duffield T.F. and Dohoo I.R. (2009). Invited review: Use of meta-analysis in animal health and reproduction: methods and applications. J. Dairy Sci. 92, 3545-3565.

Liao X.D., Lu L. and Li S.F. (2012). Effects of selenium source and level on growth performance, tissue selenium concentrations, antioxidation, and immune functions of heat-stressed broilers. Biol. Trace Elem. Res. 150, 158-165.

Liu A.Y. (2019). Research progress of microelement selenium application in sheep production. Chinese J. Anim. Nutr. 31, 78-81.

Mahan D.C., Cline T.R and Richert B. (1999). Effects of dietary levels of selenium-enriched yeast and sodium selenite as selenium sources fed to growing-finishing pigs on performance, tissue selenium, serum glutathione peroxidase activity, carcass characteristics, and loin quality. J. Anim. Sci. 77, 2172-2179.

Medeiros D.M. (2016). Copper, iron, and selenium dietary deficiencies negatively impact skeletal integrity: A review. Exp. Biol. Med. 241, 1316-1322.

NRC. (1994). Nutrient Requirements of Poultry, 9^th Rev. Ed. National Academy Press, Washington, DC., USA.

Olanrewaju H.A., Purswell J.L., Collier S.D. and Branton S.L. (2010). Effect of ambient temperature and light intensity on physiological reactions of heavy broiler chickens. Poult. Sci. 89, 2668-2677.

Payne R.L. and Southern L.L. (2005). Comparison of inorganic and organic Se sources for broilers. Poult. Sci. 84(6), 898-902.

Proszkowiec-Weglarz M. and Angel R. (2013). Calcium and phospho­rus metabolism in broilers: Effect of homeostatic mechanism on calcium and phosphorus digestibility. J. Appl. Poult. Res. 22, 609-627.

Rahimi S., Farhadi D. and Valipour A.R. (2011). Effect of organic and inorganic selenium sources and vitamin E on broiler performance and carcass characteristicsin heat stress condition. Anim. Sci. J. (Pajouhesh and Sazandegi). 91, 25-35.

Rao S.V.R., Prakash B., Raju M.V.L.N., Panda A.K, Poonan S. and Murthy O.K. (2013). Effect of supplementing organic selenium on performance, carcass traits, oxidative parameters and immune responses in commercial broiler chickens. Asian-Australasian J. Anim. Sci. 26(2), 247-252.

Rao S.V.R., Prakash B., Raju M.V.L.N., Panda A.K. and Kumari R.K. (2016). Effect of supplementing organic forms of zinc, selenium and chromium on performance, anti-oxidant, and immune responses in broiler chicken reared in tropical summer. Biol. Trace Elem. Res. 172, 511-520.

Ryu Y.C., Rhee M.S., Lee K.M. and Kim, B.C. (2005). Effects of different levels of dietary supplemental Se on performance, lipid oxidation, and color stability of broiler chicks. Poult. Sci. 84(5), 809-815.

Safiullah N., Chand N., Khan R.U., Naz S., Ahmad M. and Gul S. (2019). Effect of ginger (Zingiber officinale) and organic selenium on growth dynamics, blood malondialdehyde and paraoxonase in broilers exposed to heat stress. J. Appl. Anim. Res. 47)1), 212-216.

Sochor J., Pohanka M., Ruttkay-Nedecky B., Zitka O., Hynek D., Mares P., Zeman L., Adam V. and Kizek R. (2012). Effect of selenium in organic and inorganic form on liver, kidney, brain, and muscle of Wistar rats. Cent. Eur. J. Chem. 10, 1-12.

Suchy P., Strakova E. and Herzig I. (2014). Selenium in poultry nutrition: A review. Czech J. Anim. Sci. 59(11), 495-503.

Sun H., Zhao L., Xu Z., Demarco M., Briens M., Yan X.H. and Sun L.H. (2011). Hydroxy-selenomethionine improves the selenium status and helps to maintain broiler performances under a high stocking density and heat stress conditions through a better redox and immune response. Antioxidants. 10, 1542-1549.

Surai P.F., Kochish I.I., Fisinin V.I. and Velichko O.A. (2012). Selenium in poultry nutrition: From sodium selenite to organic selenium sources. J. Poult. Sci. 55, 79-93.

Upton J.R., Edens F.W. and Ferket P.R. (2008). Se yeast effect on broiler performance. Int. J. Poult. Sci. 7(8), 798-805.

Wang Y.B. and Xu B.H. (2008). Effect of different selenium source (sodium selenite and selenium yeast) on broiler chickens. Anim. Feed Sci Technol. 144, 306-314.

Yoon I., Werner T.M. and Butler J.M. (2007). Effect of source and concentration of selenium on growth performance and selenium retention in broiler chickens. Poult. Sci. 86, 727-730.

Zhang Z.Y., Jia G.Q., Zuo J.J., Zhang Y., Lei J., Ren L. and Feng D.Y. (2012). Effects of constant and cyclic heat stress onmuscle metabolism and meat quality of broiler breast fillet and thigh meat. Poult. Sci. 91, 2931-2937.